急性心肌梗死：端粒酶治疗的心脏保护作用。
Acute myocardial infarction: 'telomerasing' for cardioprotection.
机构信息
Research Institute, Hospital 12 de Octubre ('i+12'), Avda de Córdoba s/n, 28041 Madrid, Spain.
Research Institute, Hospital 12 de Octubre ('i+12'), Avda de Córdoba s/n, 28041 Madrid, Spain; Universidad Europea and Research Institute, Hospital 12 de Octubre ('i+12'), 28670 Villaviciosa de Odón, Madrid, Spain.
出版信息
Trends Mol Med. 2015 Apr;21(4):203-5. doi: 10.1016/j.molmed.2015.02.001. Epub 2015 Feb 25.
Reactivating the telomerase gene through gene therapy after acute myocardial infarction (AMI) has been recently reported to improve survival in mice. Given that regular physical exercise also activates this gene, therapeutic and lifestyle interventions targeting telomerase need to be explored as possible additions to the current armamentarium for myocardial regeneration.
最近有研究报道，通过基因治疗在急性心肌梗死（AMI）后激活端粒酶基因可以提高小鼠的存活率。鉴于有规律的体育锻炼也能激活该基因，因此需要探索针对端粒酶的治疗和生活方式干预措施，作为心肌再生现有手段的补充。
Zotero 插件