Orbai Ana-Maria, Halls Serena, Hewlett Sarah, Bartlett Susan J, Leong Amye L, Bingham Clifton O
J Rheumatol. 2015 Nov;42(11):2182-4. doi: 10.3899/jrheum.141172. Epub 2015 Mar 1.
Stiffness was endorsed within the rheumatoid arthritis (RA) flare core domain set at the previous Outcome Measures in Rheumatology meeting (OMERACT 11). Two stiffness breakout groups at the present OMERACT 12 RA flare workshop discussed results of new qualitative studies in RA stiffness.
Results from 2 independent studies of RA stiffness were presented to breakout group participants, followed by group discussions about stiffness measurement.
Both studies identified stiffness as complex, variable with the level of disease activity, and as encompassing concepts of impact, intensity, timing, location, and duration. That stiffness has an effect on multiple dimensions of health was a common finding. Participants agreed that stiffness is an important aspect of RA flare. Whether measuring only morning stiffness duration, the traditional approach in RA, was sufficient in coverage of the concept was unclear. Groups agreed that more research on stiffness measurement is needed considering the importance patients place on the effect of stiffness.
Results from independent studies highlight stiffness effect as an important feature of RA, in addition to intensity, timing, location, and duration. Additional work is needed to identify optimal ways to assess stiffness in RA and other rheumatologic diseases.
在之前的风湿病结局评估会议(OMERACT 11)上,僵硬被纳入类风湿关节炎(RA)病情活动核心领域集。在本次OMERACT 12 RA病情活动研讨会上,两个僵硬分组讨论了关于RA僵硬的新定性研究结果。
将两项关于RA僵硬的独立研究结果展示给分组参与者,随后进行关于僵硬测量的小组讨论。
两项研究均确定僵硬是复杂的,随疾病活动水平而变化,并且涵盖影响、强度、时间、部位和持续时间等概念。僵硬对健康的多个维度有影响是一个共同的发现。参与者一致认为僵硬是RA病情活动的一个重要方面。仅测量传统的RA晨僵持续时间是否足以涵盖这一概念尚不清楚。各小组一致认为,考虑到患者对僵硬影响的重视程度,需要对僵硬测量进行更多研究。
独立研究结果突出了僵硬影响作为RA的一个重要特征,此外还有强度、时间、部位和持续时间。需要开展更多工作来确定评估RA和其他风湿性疾病中僵硬的最佳方法。