Zapf S, Scherberich J E
Institut für klinische Strahlenkunde, Johannes Gutenberg-Universität, Mainz.
Rontgenblatter. 1989 Oct;42(10):424-7.
In 50 patients with healthy kidneys the excretion of tubular enzymes was determined quantitatively before and after administration of an ionic and a non-ionic contrast medium and compared intra-individually. Both preparations produced a highly significant increase in enzyme levels to about twice the initial value, the increase being significantly lower with the non-ionic contrast medium. This effect was fully reversible within 24 hours. No noticeable change was seen within the examination period of 48 hours in respect of creatinine and creatinine clearance levels.
在50例肾脏健康的患者中，在给予离子型和非离子型造影剂之前和之后定量测定肾小管酶的排泄情况，并进行个体内比较。两种制剂均使酶水平显著升高至初始值的两倍左右，非离子型造影剂引起的升高显著较低。这种效应在24小时内完全可逆。在48小时的检查期内，肌酐和肌酐清除率水平未见明显变化。
