Yen Yung-Feng, Chou Pesus, Lin Yu-Shiuan, Deng Chung-Yeh
Section of Infectious Diseases, Taipei City Hospital, Taipei, Taiwan, ROC; Community Medicine Research Center and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan, ROC.
Community Medicine Research Center and Institute of Public Health, National Yang-Ming University, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2015 May;78(5):292-8. doi: 10.1016/j.jcma.2015.01.001. Epub 2015 Feb 26.
Health-related quality of life (HRQOL) is widely used as an indicator of health status. However, few studies have examined predictors of HRQOL among injection drug users (IDUs). We investigated factors associated with HRQOL among IDUs in Taiwan.
In this cross-sectional study, recruited IDUs completed an HRQOL-related interview at methadone clinics in Taipei during 2012-2013. Multiple linear regression was used to identify factors associated with HRQOL.
Of 802 eligible participants, 85.4% were male; mean (SD) age was 44.7 (8.7) years. Mean scores for physical, psychological, social, and environmental HRQOL were 13.2, 11.8, 12.5, and 12.5, respectively. In multivariate analysis, social support was significantly associated with better HRQOL in all domains (β = 0.56, 0.87, 0.83, and 0.64, respectively), while obtaining most income from temporary jobs or other noncriminal sources was significantly associated with worse HRQOL in all domains (β = -1.00, -1.03, -1.15, and -1.22, respectively). Receiving methadone treatment was associated with good physical and psychological HRQOL (β = 1.47 and 0.79, respectively), while history of drug overdose (β = -0.40 and -0.53, respectively), history of cutaneous abscess (β = -0.45 and -0.53, respectively), and human immunodeficiency virus (HIV) positivity (β = -0.41 and -0.58, respectively) were associated with lower physical and psychological HRQOL. Male sex (β = -0.64 and -0.70, respectively) and a greater number of incarcerations (β = -0.11 and -0.12, respectively) were associated with poor social and environmental HRQOL.
Poor HRQOL was associated with a number of factors among IDUs at methadone clinics in Taipei, Taiwan. To improve HRQOL in this population, future programs should focus on IDUs with a history of drug overdose. In addition, methadone programs and social support should be integrated to improve HRQOL among this socially marginalized population.
健康相关生活质量（HRQOL）被广泛用作健康状况的指标。然而，很少有研究探讨注射吸毒者（IDUs）中HRQOL的预测因素。我们调查了台湾IDUs中与HRQOL相关的因素。
在这项横断面研究中，招募的IDUs于2012 - 2013年期间在台北的美沙酮诊所完成了一次与HRQOL相关的访谈。采用多元线性回归来确定与HRQOL相关的因素。
在802名符合条件的参与者中，85.4%为男性；平均（标准差）年龄为44.7（8.7）岁。身体、心理、社会和环境HRQOL的平均得分分别为13.2、11.8、12.5和12.5。在多变量分析中，社会支持在所有领域均与更好的HRQOL显著相关（β分别为0.56、0.87、0.83和0.64），而大部分收入来自临时工作或其他非犯罪来源与所有领域较差的HRQOL显著相关（β分别为 - 1.00、 - 1.03、 - 1.15和 - 1.
