Nag Shudeshna, Weinstein Miriam, Greenberg Saul
Pediatric Medicine Division, Sick Kids Hospital, Toronto, Ontario, Canada.
Pediatr Rev. 2015 Mar;36(3):e8-10. doi: 10.1542/pir.36-3-e8.
Doxycycline is a classically implicated cause of phototoxic reactions. Photo-onycholysis is a rare manifestation of phototoxicity. Nail changes may typically include nail pain, subungual hemorrhages, or distal onycholysis. Self-resolution can be expected in 3 to 6 months. Patients prescribed doxycycline should be counseled about the potential for phototoxicity and the need for appropriate sun protection while taking the medication.
强力霉素是经典的引起光毒性反应的原因。光甲脱离是光毒性的一种罕见表现。指甲变化通常可能包括指甲疼痛、甲下出血或远端甲脱离。预计3至6个月可自行缓解。应告知服用强力霉素的患者有关光毒性的可能性以及服药期间进行适当防晒的必要性。
