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与乳房植入物相关的间变性大细胞淋巴瘤

Anaplastic large cell lymphoma associated with breast implants.

作者信息

Ravi-Kumar Shalini, Sanaei Omid, Vasef Mohammad, Rabinowitz Ian, Fekrazad Mohammad Houman

机构信息

University of New Mexico Cancer Center, Albuquerque, NM, USA.

Razi Hospital, Rasht, Iran.

出版信息

World J Plast Surg. 2012 Jan;1(1):30-5.

PMID:25734041
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4344963/
Abstract

A forty two years old woman with a history of bilateral breast augmentation for cosmetic reasons was presented for poor healing of the surgical site. Tissue and periprosthetic fluid were removed from the wound site revealing an atypical lymphoid infiltrate. Subsequently the patient developed axillary lymph adenopathy. Excisional biopsy was performed. Flow cytometry was non-diagnostic. She continued to heal poorly and eventually had removal of implant during a simple mastectomy. A nodular area in the breast specimen showed ALK negative anaplastic large cell lymphoma (ALCL). The patient was treated in the private section, with only a pathology consultation being done at our institution (Figures 1-3).

摘要

一名42岁因美容原因进行双侧隆胸手术的女性,因手术部位愈合不良前来就诊。从伤口部位取出组织和假体周围液体,发现有非典型淋巴样浸润。随后患者出现腋窝淋巴结病。进行了切除活检。流式细胞术未能确诊。她的伤口持续愈合不佳,最终在单纯乳房切除术中取出了植入物。乳房标本中的一个结节区域显示为ALK阴性间变性大细胞淋巴瘤(ALCL)。该患者在私立科室接受治疗,仅在我们机构进行了病理会诊(图1-3)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/90d5e579ea7c/wjps-1-030-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/7c90e28a951c/wjps-1-030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/5ae2051cde83/wjps-1-030-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/90d5e579ea7c/wjps-1-030-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/7c90e28a951c/wjps-1-030-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/5ae2051cde83/wjps-1-030-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8fff/4344963/90d5e579ea7c/wjps-1-030-g003.jpg

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本文引用的文献

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Anaplastic large T-cell lymphoma and breast implants: a review of the literature.间变大细胞淋巴瘤与乳房植入物:文献回顾。
Plast Reconstr Surg. 2011 Sep;128(3):651-661. doi: 10.1097/PRS.0b013e318221db81.
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A patient death attributable to implant-related primary anaplastic large cell lymphoma of the breast.可归因于乳房植入物相关原发性间变大细胞淋巴瘤的患者死亡。
Plast Reconstr Surg. 2011 Sep;128(3):112e-118e. doi: 10.1097/PRS.0b013e318221db96.
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US FDA review indicates possible association between breast implants and a rare cancer.
乳房植入物相关间变性大细胞淋巴瘤:一例报告并文献复习
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Breast implant-associated, ALK-negative, T-cell, anaplastic, large-cell lymphoma: establishment and characterization of a model cell line (TLBR-1) for this newly emerging clinical entity.乳腺植入物相关、ALK 阴性、T 细胞、间变性、大细胞淋巴瘤:该新兴临床实体的模型细胞系(TLBR-1)的建立和鉴定。
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Anaplastic large cell lymphoma and breast implants: a systematic review.间变大细胞淋巴瘤与乳房植入物:系统性回顾。
Plast Reconstr Surg. 2011 Jun;127(6):2141-2150. doi: 10.1097/PRS.0b013e3182172418.
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Rare lymphoid malignancies of the breast: a report of two cases illustrating potential diagnostic pitfalls.乳腺罕见淋巴样恶性肿瘤:两例报告,说明潜在的诊断陷阱。
J Hematop. 2009 Aug 20;2(4):237-44. doi: 10.1007/s12308-009-0043-y.
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Anaplastic large cell lymphoma involving the breast: a clinicopathologic study of 6 cases and review of the literature.乳腺间变性大细胞淋巴瘤:6例临床病理研究及文献复习
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