Ehsan Seema M, George Steven C
Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, 2400 Engineering Hall, Irvine, CA 92697, USA.
Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697, USA; The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, 2400 Engineering Hall, Irvine, CA 92697, USA; Biomedical Engineering, University of California, 3120 Natural Sciences II, Irvine, CA 92697, USA; Department of Medicine, University of California, 333 City Blvd. West, Suite 400, Orange, CA 92868, USA.
J Biosci Bioeng. 2015 Sep;120(3):347-50. doi: 10.1016/j.jbiosc.2015.01.017. Epub 2015 Feb 24.
A combined experimental and mathematical model of intermittent hypoxia (IH) conditioned engineered tissue was used to characterize the effects of IH on the formation of in vitro vascular networks. Results showed that the frequency of hypoxic oscillations has pronounced influence on the vascular response of endothelial cells and fibroblasts.
采用间歇性缺氧（IH）预处理工程组织的联合实验和数学模型，以表征IH对体外血管网络形成的影响。结果表明，缺氧振荡频率对内皮细胞和成纤维细胞的血管反应有显著影响。
