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J Clin Diagn Res. 2015 Jan;9(1):FL01. doi: 10.7860/JCDR/2015/11092.5383. Epub 2015 Jan 1.
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Pharmacoepidemiol Drug Saf. 2015 Oct;24(10):1042-8. doi: 10.1002/pds.3842. Epub 2015 Aug 2.
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A case-based approach to evaluating azithromycin use and cardiovascular risks.一种基于病例的方法来评估阿奇霉素的使用情况和心血管风险。
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J Pharmacol Sci. 2018 Nov;138(3):198-202. doi: 10.1016/j.jphs.2018.10.003. Epub 2018 Oct 17.
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Is cardiovascular risk a concern when prescribing azithromycin?开具阿奇霉素处方时,心血管风险是否需要关注?
JAAPA. 2017 Jan;30(1):11-13. doi: 10.1097/01.JAA.0000511033.34198.95.
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[LONG TERM TREATMENT WITH MACROLIDES IN CHRONIC LUNG DISEASES].[大环内酯类药物在慢性肺部疾病中的长期治疗]
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Adverse effects, pharmacological interactions, and cardiovascular drugs in COVID-19 treatment.在 COVID-19 治疗中药物的不良反应、药物相互作用和心血管药物。
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本文引用的文献

1
Azithromycin and the risk of cardiovascular death.阿奇霉素与心血管死亡风险。
N Engl J Med. 2012 May 17;366(20):1881-90. doi: 10.1056/NEJMoa1003833.
2
Azithromycin-induced QT prolongation in elderly patient.阿奇霉素致老年患者QT间期延长
Acta Biomed. 2006 Apr;77(1):30-2.
3
A case of QT-interval prolongation precipitated by azithromycin.一例由阿奇霉素引发的QT间期延长病例。
N Z Med J. 2003 Nov 7;116(1185):U666.
4
Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes.尽管大环内酯类抗生素导致的QT间期延长相似,但它们的促心律失常潜力却不同:快速复极3期可预防早期后除极和尖端扭转型室速。
J Pharmacol Exp Ther. 2002 Oct;303(1):218-25. doi: 10.1124/jpet.102.037911.
5
Azithromycin modulates neutrophil function and circulating inflammatory mediators in healthy human subjects.阿奇霉素可调节健康人体受试者的中性粒细胞功能和循环炎症介质。
Eur J Pharmacol. 2002 Aug 30;450(3):277-289. doi: 10.1016/s0014-2999(02)02042-3.
6
Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics.大环内酯类抗生素对人类心脏钾通道——人类醚-去极化相关基因(HERG)的阻断作用。
J Pharmacol Exp Ther. 2002 Jul;302(1):320-7. doi: 10.1124/jpet.302.1.320.
7
The newer macrolides: azithromycin and clarithromycin.新型大环内酯类药物:阿奇霉素和克拉霉素。
Infect Dis Clin North Am. 2000 Jun;14(2):449-62, x. doi: 10.1016/s0891-5520(05)70257-9.
8
Pharmacodynamics of macrolides, azalides, and streptogramins: effect on extracellular pathogens.大环内酯类、氮杂内酯类和链阳菌素类的药效学:对细胞外病原体的作用
Clin Infect Dis. 1998 Jul;27(1):28-32. doi: 10.1086/514619.
9
Chemistry and mode of action of macrolides.大环内酯类药物的化学性质及作用方式。
J Antimicrob Chemother. 1993 Mar;31 Suppl C:1-9. doi: 10.1093/jac/31.suppl_c.1.

Risk of cardiovascular effects with azithromycin.

作者信息

Kumaresan Ramachandran, Palaian Subish, Thapa Santosh, Shankar Pathiyil Ravi

机构信息

Tutor, Department of Pharmacology / Hospital and Clinical Pharmacy, College of Medical Sciences , Bharatpur, Chitwan, Nepal .

Associate Professor, Department of Pharmacology/Hospital and Clinical Pharmacy, College of Medical Sciences , Bharatpur, Chitwan, Nepal .

出版信息

J Clin Diagn Res. 2015 Jan;9(1):FL01. doi: 10.7860/JCDR/2015/11092.5383. Epub 2015 Jan 1.

DOI:10.7860/JCDR/2015/11092.5383
PMID:25738005
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4347096/
Abstract
摘要