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COVID-19 infections and outcomes in a live registry of heart failure patients across an integrated health care system.在一个综合医疗保健系统中,心力衰竭患者的实时注册中 COVID-19 感染和结果。
PLoS One. 2020 Sep 30;15(9):e0238829. doi: 10.1371/journal.pone.0238829. eCollection 2020.
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Azithromycin and COVID-19: Prompt early use at first signs of this infection in adults and children, an approach worthy of consideration.阿奇霉素与 COVID-19:在成人和儿童出现感染迹象的早期即开始使用阿奇霉素,这种治疗方法值得考虑。
Dermatol Ther. 2020 Jul;33(4):e13785. doi: 10.1111/dth.13785. Epub 2020 Jul 12.
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A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.羟氯喹作为 COVID-19 暴露后预防的随机试验。
N Engl J Med. 2020 Aug 6;383(6):517-525. doi: 10.1056/NEJMoa2016638. Epub 2020 Jun 3.
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Remdesivir: Review of Pharmacology, Pre-clinical Data, and Emerging Clinical Experience for COVID-19.瑞德西韦:针对 COVID-19 的药理学、临床前数据和新兴临床经验综述。
Pharmacotherapy. 2020 Jul;40(7):659-671. doi: 10.1002/phar.2429. Epub 2020 Jun 28.
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Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.瑞德西韦治疗成人重症 COVID-19 的随机、双盲、安慰剂对照、多中心临床试验。
Lancet. 2020 May 16;395(10236):1569-1578. doi: 10.1016/S0140-6736(20)31022-9. Epub 2020 Apr 29.
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COVID-19 and heart failure: from infection to inflammation and angiotensin II stimulation. Searching for evidence from a new disease.COVID-19 和心力衰竭:从感染到炎症和血管紧张素 II 刺激。从一种新疾病中寻找证据。
Eur J Heart Fail. 2020 Jun;22(6):957-966. doi: 10.1002/ejhf.1871. Epub 2020 Jun 24.
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Use of Corticosteroids in Coronavirus Disease 2019 Pneumonia: A Systematic Review of the Literature.皮质类固醇在2019冠状病毒病肺炎中的应用:文献系统综述
Front Med (Lausanne). 2020 Apr 24;7:170. doi: 10.3389/fmed.2020.00170. eCollection 2020.
8
The trinity of COVID-19: immunity, inflammation and intervention.COVID-19 的三位一体:免疫、炎症和干预。
Nat Rev Immunol. 2020 Jun;20(6):363-374. doi: 10.1038/s41577-020-0311-8. Epub 2020 Apr 28.
9
Covid-19 treatment update: follow the scientific evidence.新冠病毒疾病治疗进展:遵循科学证据。
J Thromb Thrombolysis. 2020 Jul;50(1):43-53. doi: 10.1007/s11239-020-02120-9.
10
Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area.在纽约市地区,5700 名因 COVID-19 住院的患者的特征、合并症和结局。
JAMA. 2020 May 26;323(20):2052-2059. doi: 10.1001/jama.2020.6775.

在 COVID-19 治疗中药物的不良反应、药物相互作用和心血管药物。

Adverse effects, pharmacological interactions, and cardiovascular drugs in COVID-19 treatment.

机构信息

Department of Clinical Cardiology, National Institute Cardiology Ignacio Chávez, Mexico City, Mexico.

Cardiovascular Post-Surgical Unit, National Institute of Child Health, Lima, Peru.

出版信息

Arch Cardiol Mex. 2021 Dec 20;91(Suplemento COVID):079-085. doi: 10.24875/ACM.20000234.

DOI:10.24875/ACM.20000234
PMID:33459727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10161861/
Abstract

In severe coronavirus disease (COVID)-19 patients, an extraordinary systemic inflammatory response is seen. It could impact in multiple organ disorders, specially a severe myocardial injury, an acute myocarditis results in focal or global myocardial inflammation and necrosis. Those events can be present in healthy subjects or cardiovascular (CV) patients. It is clinically associated with ventricular dysfunction exacerbation or worsening and tachyarrhythmias. It is also related to a poor outcome for CV patients with ischemic heart disease, hypertensión, and heart failure. COVID-19 patients require multiple and complex treatment that alleviates symptoms, the vast variety of agents interacts with diseases and CV drugs. Our purpose is to correlate in guidance synopsis: Adverse effects, pharmacological interactions, and CV drugs in COVID-19 treatment.

摘要

在严重的冠状病毒病(COVID-19)患者中,会出现异常的全身炎症反应。它可能会影响多个器官的功能紊乱,特别是严重的心肌损伤,急性心肌炎会导致局灶性或全球性心肌炎症和坏死。这些事件可能发生在健康受试者或心血管(CV)患者中。它与心室功能障碍加重或恶化以及心动过速性心律失常有关。它也与患有缺血性心脏病、高血压和心力衰竭的 CV 患者的不良预后相关。COVID-19 患者需要接受多种复杂的治疗以缓解症状,大量的药物与疾病和 CV 药物相互作用。我们的目的是在指南摘要中关联:COVID-19 治疗中的不良反应、药物相互作用和 CV 药物。