Lalitha Ch, Manjula M, Srikant K, Goyal Stuti, Tanveer Shahela
Senior Lecturer, Department of Oral Medicine and Radiology, Sri Sai College of Dental Surgery , Vikarabad,Telanagana, India .
Professor, Department of Oral Medicine and Radiology, Gandhi Hospitals , Hyderabad, India .
J Clin Diagn Res. 2015 Jan;9(1):ZD28-30. doi: 10.7860/JCDR/2015/10985.5481. Epub 2015 Jan 1.
Langerhan's Cell Histiocytosis (LCH) is disorders which include abnormalities that result from abnormal proliferation of langerhan's cells or their precursors. LCH is clinically classified into three types-eosinophilic granuloma, Hand Schuller Christian disease and Abt-Letterer- Siwe disease. It is usually manifested in childhood as well as in adulthood. The clinical manifestations are the result of the accumulation and infilteration of the langerhan cells in organs and tissues. Here is a rare case report of 6-year-old boy with extraoral manifestation of exopthalmic right eye and oral manifestation of mobility of teeth and with typical radiological findings. Basing on the clinical, radiological and histopathological examination the diagnosis of Hand Schuller Christian Disease was given.
朗格汉斯细胞组织细胞增多症(LCH)是一类疾病,包括由朗格汉斯细胞或其前体细胞异常增殖导致的异常情况。LCH临床分为三种类型——嗜酸性肉芽肿、汉-许-克病和勒-雪病。它通常在儿童期和成年期均可出现。临床表现是朗格汉斯细胞在器官和组织中积聚及浸润的结果。本文报告一例罕见病例,一名6岁男孩,表现为右眼眼球突出的口外症状以及牙齿松动的口腔症状,并伴有典型的影像学表现。基于临床、影像学和组织病理学检查,诊断为汉-许-克病。