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Subacute multicranial neuropathy revealing an early case of meningeal syphilis.

作者信息

Casolla Barbara, Ristori Giovanni, Romano Andrea, Bozzao Alessandro, Orzi Francesco

机构信息

NeSMOS Department (Neurosciences, Mental Health and Sensory Organs), School of Medicine and Psychology, University of Rome "La Sapienza", UOC Neurology, Sant'Andrea Hospital, Rome, Italy,

出版信息

Neurol Sci. 2015 Jun;36(6):1033-4. doi: 10.1007/s10072-015-2125-1. Epub 2015 Mar 5.

DOI:10.1007/s10072-015-2125-1
PMID:25739944
Abstract

We report a case of neurosyphilis presenting with meningitis and subacute multicranial neuropathy in a young immune-competent man. Signs of primary and secondary stages of syphilitic infection occurred almost contemporarily in our patient. MRI revealed the involvement of several cranial nerves. CSF examination proved to be diagnostic. Syphilitic meningitis should be considered among the differential diagnoses of subacute, multicranial neuropathy, or skull base meningitis. The clinical course of this patient shows that early diagnosis and treatment warrant a good neurological outcome.

摘要

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本文引用的文献

1
Temporal lobe abnormalities in neurosyphilis.神经梅毒中的颞叶异常。
Pract Neurol. 2014 Dec;14(6):449-50. doi: 10.1136/practneurol-2014-000927. Epub 2014 Aug 28.
2
Primary and secondary syphilis--United States, 2005-2013.一期和二期梅毒——美国,2005-2013 年。
MMWR Morb Mortal Wkly Rep. 2014 May 9;63(18):402-6.
3
Clinical spectrum of neurosyphilis among HIV-negative patients in the modern era.神经梅毒在现代 HIV 阴性患者中的临床谱系。
Dermatology. 2013;226(2):148-56. doi: 10.1159/000347109. Epub 2013 Apr 19.
4
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5
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Sex Transm Infect. 2011 Apr;87(3):191-8. doi: 10.1136/sti.2009.040139. Epub 2011 Jan 24.
6
Current clinical spectrum of neurosyphilis in immunocompetent patients.免疫功能正常患者神经梅毒的当前临床谱。
Eur Neurol. 2004;52(1):29-35. doi: 10.1159/000079391. Epub 2004 Jun 28.
7
Acquired syphilis in adults.成人获得性梅毒。
N Engl J Med. 1992 Apr 16;326(16):1060-9. doi: 10.1056/NEJM199204163261606.