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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Buzzell G R, Chen Z, Vaughan M K, Reiter R J

Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.

Comp Biochem Physiol A Comp Physiol. 1989;94(3):427-9. doi: 10.1016/0300-9629(89)90116-3.

Indole metabolism and porphyrin content of the Harderian glands of the male Syrian hamster were measured as functions of drug-induced hypothyroidism and exposure to cold conditions. 2. Harderian gland N-acetyltransferase (NAT) activity was reduced from control levels by hypothyroidism induced by methimazole; exposure to cold had no effect on NAT activity. 3. Immunoreactive melatonin in the Harderian glands was unaffected by the state of thyroid secretion. However, immunoreactive melatonin content declined after 180 and 270 min, at 4 degrees C, suggesting that Harderian gland melatonin may be involved in thermoregulation. 4. Porphyrin content of the Harderian glands was not affected by either thyroid secretion or cold.

测定了雄性叙利亚仓鼠哈德氏腺的吲哚代谢和卟啉含量，作为药物诱导的甲状腺功能减退和暴露于寒冷环境的函数。2. 甲巯咪唑诱导的甲状腺功能减退使哈德氏腺N-乙酰转移酶（NAT）活性从对照水平降低；暴露于寒冷对NAT活性没有影响。3. 哈德氏腺中的免疫反应性褪黑素不受甲状腺分泌状态的影响。然而，在4℃下180和270分钟后，免疫反应性褪黑素含量下降，这表明哈德氏腺褪黑素可能参与体温调节。4. 哈德氏腺的卟啉含量不受甲状腺分泌或寒冷的影响。

Buzzell G R, Chen Z, Vaughan M K, Reiter R J

Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio 78284.

Comp Biochem Physiol A Comp Physiol. 1989;94(3):427-9. doi: 10.1016/0300-9629(89)90116-3.

Indole metabolism and porphyrin content of the Harderian glands of the male Syrian hamster were measured as functions of drug-induced hypothyroidism and exposure to cold conditions. 2. Harderian gland N-acetyltransferase (NAT) activity was reduced from control levels by hypothyroidism induced by methimazole; exposure to cold had no effect on NAT activity. 3. Immunoreactive melatonin in the Harderian glands was unaffected by the state of thyroid secretion. However, immunoreactive melatonin content declined after 180 and 270 min, at 4 degrees C, suggesting that Harderian gland melatonin may be involved in thermoregulation. 4. Porphyrin content of the Harderian glands was not affected by either thyroid secretion or cold.

测定了雄性叙利亚仓鼠哈德氏腺的吲哚代谢和卟啉含量，作为药物诱导的甲状腺功能减退和暴露于寒冷环境的函数。2. 甲巯咪唑诱导的甲状腺功能减退使哈德氏腺N-乙酰转移酶（NAT）活性从对照水平降低；暴露于寒冷对NAT活性没有影响。3. 哈德氏腺中的免疫反应性褪黑素不受甲状腺分泌状态的影响。然而，在4℃下180和270分钟后，免疫反应性褪黑素含量下降，这表明哈德氏腺褪黑素可能参与体温调节。4. 哈德氏腺的卟啉含量不受甲状腺分泌或寒冷的影响。