Wang Zhi-Gang, Zhang Yong, Zeng Xian-Dong, Zhang Tie-Hui, Zhu Qi-Dong, Liu De-Long, Qiao Yun-Yu, Mu Nan, Yin Zhi-Tao
Zhi-Gang Wang, Yong Zhang, Xian-Dong Zeng, Tie-Hui Zhang, Qi-Dong Zhu, De-Long Liu, Yun-Yu Qiao, Nan Mu, Zhi-Tao Yin, The 5 Department of Anorectal Disease, Shenyang Coloproctology Hospital, Shenyang 110002, Liaoning Province, China.
World J Gastroenterol. 2015 Feb 28;21(8):2490-6. doi: 10.3748/wjg.v21.i8.2490.
To compare the effects and postoperative complications between tissue selecting therapy stapler (TST) and Milligan-Morgan hemorrhoidectomy (M-M).
Four hundred and eighty patients with severe prolapsing hemorrhoids, who were admitted to the Shenyang Coloproctology Hospital between 2009 and 2012, were randomly divided into observation (n=240) and control (n=240) groups. Hemorrhoidectomies were performed with TST in the observation group and with the M-M technique in the control group. The therapeutic effects, operation security, and postoperative complications in the two groups were compared. The immediate and long-term complications were assessed according to corresponding criteria. Pain was assessed on a visual analogue scale. The efficacy was assessed by specialized criteria. The follow-up was conducted one year after the operation.
The total effective rates of the observation and control groups were 99.5% (217/218) and 98.6% (218/221) respectively; the difference was not statistically significant (P=0.322). Their were significant differences between observation and control groups in intraoperative blood loss (5.07±1.14 vs 2.45±0.57, P=0.000), pain (12 h after the surgery: 5.08±1.62 vs 7.19±2.01, P=0.000; at first dressing change: 2.64±0.87 vs 4.34±1.15, P=0.000; first defecation: 3.91±1.47 vs 5.63±1.98, P=0.001), urine retention (n=22 vs n=47, P=0.001), anal pendant expansion after the surgery (2.35±0.56 vs 5.16±1.42, P=0.000), operation time (18.3±5.6 min vs 29.5±8.2 min, P=0.000), and the length of hospital stay (5.3±0.6 d vs 11.4±1.8 d, P=0.000). Moreover TST showed significant reductions compared to M-M in the rates of long-term complications such as fecal incontinence (n=3 vs n=16, P=0.003), difficult bowel movement (n=1 vs n=9, P=0.011), intractable pain (n=2 vs n=12, P=0.007), and anal discharge (n=3 vs n=23, P=0.000).
TST for severe prolapsing hemorrhoids is a satisfactory technique for more rapid recovery, lower complication rates, and higher operation security.
比较组织选择性吻合器痔上黏膜环切术(TST)与Milligan-Morgan痔切除术(M-M)的疗效及术后并发症。
选取2009年至2012年期间收治于沈阳肛肠医院的480例重度脱垂性痔患者,随机分为观察组(n = 240)和对照组(n = 240)。观察组采用TST行痔切除术,对照组采用M-M技术。比较两组的治疗效果、手术安全性及术后并发症。根据相应标准评估近期和远期并发症。采用视觉模拟评分法评估疼痛程度。依据专业标准评估疗效。术后1年进行随访。
观察组和对照组的总有效率分别为99.5%(217/218)和98.6%(218/221);差异无统计学意义(P = 0.322)。观察组与对照组在术中出血量(5.07±1.14 vs 2.45±0.57,P = 0.000)、疼痛程度(术后12小时:5.08±1.62 vs 7.19±2.01,P = 0.000;首次换药时:2.64±0.87 vs 4.34±1.15,P = 0.000;首次排便时:3.91±1.47 vs 5.63±1.98,P = 0.001)、尿潴留(n = 22 vs n = 47,P = 0.001)、术后肛门坠胀(2.35±0.56 vs 5.16±1.42,P = 0.000)、手术时间(18.3±5.6分钟vs 29.5±8.2分钟,P = 0.000)及住院时间(5.3±0.6天vs 11.4±1.8天,P = 0.000)方面存在显著差异。此外,与M-M相比,TST在大便失禁(n = 3 vs n = 16,P = 0.003)、排便困难(n = 1 vs n = 9,P = 0.011)、顽固性疼痛(n = 2 vs n = 12,P = 0.007)及肛门渗液(n = 3 vs n = 23,P = 0.000)等远期并发症发生率方面显著降低。
TST治疗重度脱垂性痔是一种令人满意的技术,具有恢复更快、并发症发生率更低及手术安全性更高的特点。