Hanzlíková Hana, Plavcová Eva, Kynčl Jan, Kříž Bohumír, Kyselý Jan
Institute of Atmospheric Physics, The Czech Academy of Sciences, Boční II 1401, 141 31, Prague, Czech Republic.
Faculty of Science, Charles University, Prague, Czech Republic.
Int J Biometeorol. 2015 Nov;59(11):1673-84. doi: 10.1007/s00484-015-0974-1. Epub 2015 Mar 6.
The study examines effects of hot spells on cardiovascular disease (CVD) morbidity and mortality in the population of the Czech Republic, with emphasis on differences between ischaemic heart disease (IHD) and cerebrovascular disease (CD) and between morbidity and mortality. Daily data on CVD morbidity (hospital admissions) and mortality over 1994-2009 were obtained from national hospitalization and mortality registers and standardized to account for long-term changes as well as seasonal and weekly cycles. Hot spells were defined as periods of at least two consecutive days with average daily air temperature anomalies above the 95% quantile during June to August. Relative deviations of mortality and morbidity from the baseline were evaluated. Hot spells were associated with excess mortality for all examined cardiovascular causes (CVD, IHD and CD). The increases were more pronounced for CD than IHD mortality in most population groups, mainly in males. In the younger population (0-64 years), however, significant excess mortality was observed for IHD while there was no excess mortality for CD. A short-term displacement effect was found to be much larger for mortality due to CD than IHD. Excess CVD mortality was not accompanied by increases in hospital admissions and below-expected-levels of morbidity prevailed during hot spells, particularly for IHD in the elderly. This suggests that out-of-hospital deaths represent a major part of excess CVD mortality during heat and that for in-hospital excess deaths CVD is a masked comorbid condition rather than the primary diagnosis responsible for hospitalization.
该研究调查了热浪对捷克共和国人群心血管疾病(CVD)发病率和死亡率的影响,重点关注缺血性心脏病(IHD)和脑血管疾病(CD)之间以及发病率和死亡率之间的差异。1994年至2009年期间心血管疾病发病率(住院人数)和死亡率的每日数据来自国家住院和死亡登记册,并进行了标准化处理,以考虑长期变化以及季节性和每周周期。热浪被定义为6月至8月期间平均每日气温异常高于第95百分位数的至少连续两天的时间段。评估了死亡率和发病率相对于基线的相对偏差。热浪与所有检查的心血管病因(CVD、IHD和CD)的超额死亡率相关。在大多数人群组中,尤其是男性,CD的死亡率增加比IHD更明显。然而,在较年轻的人群(0至64岁)中,IHD出现了显著的超额死亡率,而CD没有超额死亡率。发现CD导致的死亡率的短期替代效应比IHD大得多。心血管疾病超额死亡率并未伴随着住院人数的增加,在热浪期间发病率普遍低于预期水平,尤其是老年人中的IHD。这表明院外死亡是热浪期间心血管疾病超额死亡率的主要组成部分,并且对于院内超额死亡,心血管疾病是一种隐匿的合并症,而不是导致住院的主要诊断。