Moghadamnia Mohammad Taghi, Ardalan Ali, Mesdaghinia Alireza, Naddafi Kazem, Yekaninejad Mir Saeed
Department of Disaster Public Health, School of Public Health, Tehran University of Medical Science, Tehran, Iran.
Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences; Institute for Environment Research, Tehran, Iran.
Heart Asia. 2018 Oct 22;10(2):e011068. doi: 10.1136/heartasia-2018-011068. eCollection 2018.
Our objective was to assess the relations between apparent temperature and incidence of acute coronary syndrome (ACS) in Rasht, Iran.
We used a time-series analysis to investigate the relationship between apparent temperature and hospital admission from 2005 to 2014. Distributed lag non-linear models were used to estimate the association between ACS hospitalisation and apparent temperature. To examine the high-temperature effect on ACS hospital admission, the relative risk of ACS hospital admission associated with high temperature, the 99th percentile of temperature (34.7°C) compared with the 75th percentile of temperature (26.9°C), was calculated. To assess the cold effect on ACS hospital admission, the relative risk of ACS hospital admission associated with cold temperature, the first percentile of temperature (-0.2°C) compared with the 25th percentile of temperature (8.2°C), was evaluated.
The cumulative effect of hot exposure on ACS admissions was statistically significant, with a relative risk of 2.04 (95% CI 1.06 to 4.16). The cumulative effect of cold temperature on ACS admissions was found to be non-significant. The highest risk of ACS admission in women was in 38°C (RR, 2.03, 95% CI 1.04 to 4.18). The effect of hot temperature on ACS admission occurred immediately (lag 0) (RR, 1.09, 95% CI 1.001 to 1.19).
The high apparent temperature is correlated with a higher ACS admission especially on the same day. These findings may have implications for developing intervention strategies to reduce and prevent temperature-related morbidity especially in the elderly.
我们的目的是评估伊朗拉什特市体感温度与急性冠状动脉综合征(ACS)发病率之间的关系。
我们采用时间序列分析来研究2005年至2014年体感温度与住院情况之间的关系。使用分布滞后非线性模型来估计ACS住院与体感温度之间的关联。为检验高温对ACS住院的影响,计算了与高温相关的ACS住院相对风险,即将温度的第99百分位数(34.7°C)与第75百分位数(26.9°C)相比较。为评估低温对ACS住院的影响,评估了与低温相关的ACS住院相对风险,即将温度的第1百分位数(-0.2°C)与第25百分位数(8.2°C)相比较。
热暴露对ACS住院的累积影响具有统计学意义,相对风险为2.04(95%置信区间为1.06至4.16)。发现低温对ACS住院的累积影响不显著。女性ACS住院的最高风险出现在38°C时(相对风险,2.03,95%置信区间为1.04至4.18)。高温对ACS住院的影响立即出现(滞后0)(相对风险,1.09,95%置信区间为1.001至1.19)。
高体感温度与更高的ACS住院率相关,尤其是在同一天。这些发现可能对制定干预策略以减少和预防与温度相关的发病率具有启示意义,特别是对老年人而言。