Patel Trupti S, Shah Chintan, Shah Majal C, Shah Manoj J
Department of Pathology, Gujarat Cancer and Research Institute, M. P. Shah Cancer Hospital, Ahmadabad, Gujarat, India.
J Cytol. 2014 Oct-Dec;31(4):202-4. doi: 10.4103/0970-9371.151132.
Metastasization and distinction from mammary carcinoma is of great clinical importance because of different treatment modalities. Here, we discuss a case of stage IIIC ovarian serous carcinoma, presenting with bilateral axillary nodes metastasis after 25 months interval of its initial presentation. Increased serum CA-125 level caused clinical suspicion. Computed tomography scan of abdomen and pelvis showed no residual disease or any abdominal lymphadenopathy. Mammography of both breast were normal. Bilateral axillary nodes were noted. Guided fine needle aspiration cytology (FNAC) and biopsy of ovarian carcinoma to axillary node is a rare event. Its recogn done. Cytomorphology revealed poorly differentiated carcinoma, compatible to that of primary ovarian tumor. Thus, metastatic carcinoma to axillary node from ovary was confirmed. This case illustrates a rare metastatic presentation of ovarian carcinoma and unequivocal role of FNAC to provide rapid diagnosis and preferred to be first line diagnostic procedure.
由于治疗方式不同,转移及与乳腺癌的鉴别具有重要的临床意义。在此,我们讨论一例IIIC期卵巢浆液性癌病例,该病例在初次就诊25个月后出现双侧腋窝淋巴结转移。血清CA - 125水平升高引起临床怀疑。腹部和盆腔计算机断层扫描未发现残留病灶或任何腹部淋巴结病。双侧乳房钼靶检查正常。发现双侧腋窝淋巴结。对卵巢癌腋窝淋巴结进行引导下细针穿刺细胞学检查(FNAC)及活检是罕见的情况。已完成识别。细胞形态学显示为低分化癌,与原发性卵巢肿瘤相符。因此,确诊为卵巢癌腋窝淋巴结转移癌。该病例说明了卵巢癌一种罕见的转移表现以及FNAC在提供快速诊断方面的明确作用,且FNAC更宜作为一线诊断程序。