Department of Chemistry, Iowa State University, 2101d Hach Hall, Ames, Iowa 50011, United States.
J Am Chem Soc. 2015 Mar 25;137(11):3783-6. doi: 10.1021/jacs.5b01297. Epub 2015 Mar 17.
Photoremovable protecting groups derived from meso-substituted BODIPY dyes release acetic acid with green wavelengths >500 nm. Photorelease is demonstrated in cultured S2 cells. The photocaging structures were identified by our previously proposed strategy of computationally searching for carbocations with low-energy diradical states as a possible indicator of a nearby productive conical intersection. The superior optical properties of these photocages make them promising alternatives to the popular o-nitrobenzyl photocage systems.
源自中取代 BODIPY 染料的光致脱保护基在 >500nm 的绿光波长下释放乙酸。在培养的 S2 细胞中证明了光释放。光笼结构通过我们之前提出的策略来识别，该策略通过计算搜索具有低能量自由基态的碳正离子作为附近生产性锥形交叉的可能指标。这些光笼的优异光学性质使它们成为广受欢迎的邻硝基苄基光笼系统的有前途替代品。
