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肥胖与因良性指征进行子宫切除的手术途径趋势之间的关联。

Association between obesity and the trends of routes of hysterectomy performed for benign indications.

作者信息

Mikhail Emad, Miladinovic Branko, Velanovich Vic, Finan Michael A, Hart Stuart, Imudia Anthony N

机构信息

Departments of Obstetrics and Gynecology, Internal Medicine, and General Surgery, University of South Florida, Morsani College of Medicine, Tampa, Florida; and the Division of Gynecologic Oncology, University of South Alabama, Mitchell Cancer Institute, Mobile, Alabama.

出版信息

Obstet Gynecol. 2015 Apr;125(4):912-918. doi: 10.1097/AOG.0000000000000733.

Abstract

OBJECTIVE

To estimate the association between obesity and the recent trends of routes chosen for hysterectomy performed for benign indications in the United States.

MATERIALS AND METHODS

Using the American College of Surgeons-National Surgical Quality Improvement Project's database, patients who underwent hysterectomy for benign indications from 2005 to 2011 were identified by International Classification of Diseases, 9th Revision codes and were categorized into total abdominal hysterectomy (TAH), total vaginal hysterectomy (TVH), laparoscopically assisted vaginal hysterectomy (LAVH), and total laparoscopic hysterectomy (TLH). The patients were divided into four subgroups according to body mass index (BMI) (less than 25, 25-29.9, 30-39.9, and 40 or greater). The data were analyzed using Student's t test or χ2 and Fisher's exact test.

RESULTS

A total of 18,810 patients underwent hysterectomy for benign indications during the study period: 9,852 (52.4%) were TAH, 5,146 (27.4%) TVH, 2,296 (12.2%) LAVH, and 1,516 (8.0%) TLH. The rates of TAH increased from 45.7% in patients with ideal body weight to 62% in morbidly obese patients (P<.001). The rate of TVH and LAVH decreased from 32.7% and 13.3% in patients with ideal body weight to 17.1% and 11.7% in morbidly obese patients, respectively (P<.001 and 0.04). The rate of TLH performed was independent of BMI (P=.61). Higher BMI was associated with longer operative time (P<.001) in all routes of hysterectomy. The rates of superficial and deep wound infections were higher with increasing BMI in patients undergoing TAH (P<.001) but not with TVH (P=.26), LAVH (P=1.0), or TLH (P=.48).

CONCLUSION

Regarding hysterectomy performed for benign indications, increasing BMI was associated with increased rate of TAH and decreased rate of TVH and LAVH, but not the rate of TLH. Increasing BMI was associated with increased operative time for all subgroups and increased surgical site infection in the TAH group.

摘要

目的

评估美国因良性指征行子宫切除术的肥胖与近期手术路径选择趋势之间的关联。

材料与方法

利用美国外科医师学会-国家外科质量改进项目数据库,通过国际疾病分类第九版编码识别出2005年至2011年因良性指征行子宫切除术的患者,并将其分为经腹全子宫切除术(TAH)、经阴道全子宫切除术(TVH)、腹腔镜辅助经阴道子宫切除术(LAVH)和全腹腔镜子宫切除术(TLH)。根据体重指数(BMI)(小于25、25-29.9、30-39.9以及40或更高)将患者分为四个亚组。采用学生t检验或χ²检验及费舍尔精确检验对数据进行分析。

结果

研究期间共有18,810例患者因良性指征行子宫切除术:9,852例(52.4%)为TAH,5,146例(27.4%)为TVH,2,296例(12.2%)为LAVH,1,516例(8.0%)为TLH。TAH的比例从体重正常患者中的45.7%增至病态肥胖患者中的62%(P<0.001)。TVH和LAVH的比例分别从体重正常患者中的32.7%和13.3%降至病态肥胖患者中的17.1%和11.7%(P<0.001和0.04)。TLH的实施比例与BMI无关(P=0.61)。在所有子宫切除路径中,较高的BMI与较长的手术时间相关(P<0.001)。在接受TAH的患者中,随着BMI增加,浅表和深部伤口感染率升高(P<0.001),但在TVH(P=0.26)、LAVH(P=1.0)或TLH(P=0.48)患者中并非如此。

结论

对于因良性指征行子宫切除术而言,BMI增加与TAH比例增加以及TVH和LAVH比例降低相关,但与TLH比例无关。BMI增加与所有亚组的手术时间延长以及TAH组手术部位感染增加相关。

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