Seo Kyoung Duck, Kwak Byung Kook, Sanchez Samuel, Kim Dong Sung
IEEE Trans Nanobioscience. 2015 Apr;14(3):298-304. doi: 10.1109/TNB.2015.2402651. Epub 2015 Mar 2.
In this paper, we fabricate a flexible and location traceable micromotor, called organo-motor, assisted by microfluidic devices and with high throughput. The organo-motors are composed of organic hydrogel material, poly (ethylene glycol) diacrylate (PEGDA), which can provide the flexibility of their structure. For spatial and temporal traceability of the organo-motors under magnetic resonance imaging (MRI), superparamagnetic iron oxide nanoparticles (SPION; Fe3O4) were incorporated into the PEGDA microhydrogels. Furthermore, a thin layer of platinum (Pt) was deposited onto one side of the SPION-PEGDA microhydrogels providing geometrical asymmetry and catalytic propulsion in aqueous fluids containing hydrogen peroxide solution, H2O2. Furthermore, the motion of the organo-motor was controlled by a small external magnet enabled by the presence of SPION in the motor architecture.
在本文中，我们借助微流控装置制造了一种灵活且可定位追踪的微电机，称为有机电机，其具有高通量。有机电机由有机水凝胶材料聚（乙二醇）二丙烯酸酯（PEGDA）组成，该材料可提供其结构的灵活性。为了在磁共振成像（MRI）下对有机电机进行空间和时间追踪，将超顺磁性氧化铁纳米颗粒（SPION；Fe3O4）掺入PEGDA微水凝胶中。此外，在SPION-PEGDA微水凝胶的一侧沉积了一层薄铂（Pt），在含有过氧化氢溶液H2O2的水性流体中提供几何不对称性和催化推进力。此外，有机电机的运动由电机结构中存在的SPION启用的小型外部磁体控制。
