JCGGDB：日本糖生物学与糖技术联盟数据库。

JCGGDB: Japan Consortium for Glycobiology and Glycotechnology Database.

作者信息

Maeda Masako, Fujita Noriaki, Suzuki Yoshinori, Sawaki Hiromichi, Shikanai Toshihide, Narimatsu Hisashi

机构信息

Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), Central 2, 1-1-1 Umezono, Tsukuba, Ibaraki, 305-8568, Japan.

出版信息

Methods Mol Biol. 2015;1273:161-79. doi: 10.1007/978-1-4939-2343-4_12.

DOI:10.1007/978-1-4939-2343-4_12

PMID:25753710

Abstract

The biological significance of glycans has been widely studied and reported in the past. However, most achievements of our predecessors are not readily available in existing databases. JCGGDB is a meta-database involving 15 original databases in AIST and 5 cooperative databases in alliance with JCGG: Japan Consortium for Glycobiology and Glycotechnology. It centers on a glycan structure database and accumulates information such as glycan preferences of lectins, glycosylation sites in proteins, and genes related to glycan syntheses from glycoscience and related fields. This chapter illustrates how to use three major search interfaces (Keyword Search, Structure Search, and GlycoChem Explorer) available in JCGGDB to search across multiple databases.

摘要

聚糖的生物学意义在过去已得到广泛研究和报道。然而，我们前辈的大多数成果在现有数据库中并不容易获取。JCGGDB是一个元数据库，它包含了日本产业技术综合研究所（AIST）的15个原始数据库以及与日本糖生物学和糖技术联盟（JCGG）合作的5个数据库。它以聚糖结构数据库为核心，积累了来自糖科学及相关领域的信息，如凝集素的聚糖偏好、蛋白质中的糖基化位点以及与聚糖合成相关的基因。本章将说明如何使用JCGGDB中可用的三个主要搜索界面（关键词搜索、结构搜索和糖化学浏览器）在多个数据库中进行搜索。