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Glyco3D:结构糖科学门户网站。

Glyco3D: a portal for structural glycosciences.

作者信息

Pérez Serge, Sarkar Anita, Rivet Alain, Breton Christelle, Imberty Anne

机构信息

Centre de Recherches sur les Macromolécules Végétales, UPR5301, CNRS - Université Grenoble Alpes, BP53, 38041, Grenoble cédex 09, France.

出版信息

Methods Mol Biol. 2015;1273:241-58. doi: 10.1007/978-1-4939-2343-4_18.

Abstract

The present work describes, in a detailed way, a family of databases covering the three-dimensional features of monosaccharides, disaccharides, oligosaccharides, polysaccharides, glycosyltransferases, lectins, monoclonal antibodies against carbohydrates, and glycosaminoglycan-binding proteins. These databases have been developed with non-proprietary software, and they are open freely to the scientific community. They are accessible through the common portal called "Glyco3D" http://www.glyco3d.cermav.cnrs.fr. The databases are accompanied by a user-friendly graphical user interface (GUI) which offers several search options. All three-dimensional structures are available for visual consultations (with basic measurements possibilities) and can be downloaded in commonly used formats for further uses.

摘要

本研究详细描述了一系列数据库,内容涵盖单糖、二糖、寡糖、多糖、糖基转移酶、凝集素、抗碳水化合物单克隆抗体以及糖胺聚糖结合蛋白的三维特征。这些数据库是使用非专有软件开发的,并且对科学界免费开放。可通过名为“Glyco3D”的通用门户http://www.glyco3d.cermav.cnrs.fr访问。这些数据库配有用户友好的图形用户界面(GUI),提供多种搜索选项。所有三维结构都可供可视化查阅(具备基本测量功能),并且可以以常用格式下载以供进一步使用。

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