Luebbert Rebecca, Perez Amelia
Southern Illinois University Edwardsville, IL, USA
Southern Illinois University Edwardsville, IL, USA.
J Transcult Nurs. 2016 Sep;27(5):456-63. doi: 10.1177/1043659615575578. Epub 2015 Mar 9.
Clinical research requires representation of racially and ethnically diverse participants to accurately represent the general population. Overall life expectancy of African Americans is shorter than that of the general U.S.
Compared with the other ethnic groups in the United States, African Americans have higher rates of hypertension, stroke, obesity, and diabetes, and higher rates of mortality related to stroke and cancer. Although many health disparities exist among African Americans, they are well underrepresented in clinical research. This article provides an overview of barriers that may influence participation in clinical research among African Americans. Issues of trust, experimentation, communication, and logistics are the most commonly identified barriers. The barriers and facilitators identified in this review may be useful in the development and implementation of recruitment and research strategies that are culturally sensitive and that may enhance trust and willingness to participate among African Americans.
临床研究需要不同种族和族裔的参与者参与，以准确代表一般人群。非裔美国人的总体预期寿命低于美国普通人群。
与美国其他族裔群体相比，非裔美国人患高血压、中风、肥胖症和糖尿病的比率更高，与中风和癌症相关的死亡率也更高。尽管非裔美国人存在许多健康差异，但他们在临床研究中的代表性严重不足。本文概述了可能影响非裔美国人参与临床研究的障碍。信任、试验、沟通和后勤问题是最常被提及的障碍。本综述中确定的障碍和促进因素可能有助于制定和实施具有文化敏感性的招募和研究策略，从而增强非裔美国人的信任和参与意愿。
