Lee Andrew, Lim Adrian, Fischer Gayle
Department of Dermatology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Northern Clinical School, University of Sydney, St Leonards, New South Wales, Australia.
Australas J Dermatol. 2016 Feb;57(1):39-43. doi: 10.1111/ajd.12305. Epub 2015 Mar 5.
Vulval lichen sclerosus is an uncommon skin condition that can usually be managed with topical corticosteroids to maintain remission. However, there is a subset of patients in whom it remains recalcitrant despite treatment with super-potent topical corticosteroids. We report a case series of four patients undergoing fractional carbon dioxide laser resurfacing and one with ablative carbon dioxide laser for severe, hyperkeratotic vulval lichen sclerosus not responding to super-potent topical corticosteroids. In these patients, carbon dioxide laser was successful in achieving remission. Their vulval lichen sclerosus was subsequently able to be maintained with topical corticosteroid treatment.
外阴硬化性苔藓是一种不常见的皮肤病,通常可用外用皮质类固醇进行治疗以维持病情缓解。然而,有一部分患者尽管使用了超强效外用皮质类固醇治疗,病情仍然顽固。我们报告了一组病例,其中4例患者接受了分次二氧化碳激光换肤治疗,1例患者接受了剥脱性二氧化碳激光治疗,这些患者患有严重的、角化过度的外阴硬化性苔藓,对超强效外用皮质类固醇治疗无效。在这些患者中,二氧化碳激光成功实现了病情缓解。随后,他们的外阴硬化性苔藓能够通过外用皮质类固醇治疗得以维持。