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分次微剥脱性二氧化碳激光治疗阴茎硬化性苔藓

Fractional Micro-ablative CO2 Laser as Therapy in Penile Lichen Sclerosus.

作者信息

Campolmi Piero, Cannarozzo Giovanni, Bennardo Luigi, Clementi Alessandro, Sannino Mario, Nisticò Steven Paul

机构信息

Department of Dermatology, Università di Firenze, Florence, Italy.

Department of Dermatology, Tor Vergata University, Rome, Italy.

出版信息

J Lasers Med Sci. 2021 Oct 18;12:e61. doi: 10.34172/jlms.2021.61. eCollection 2021.

Abstract

Topical steroids remain the first-line therapy to treat lichen sclerosus (LS), but circumcision may be curative in most cases. Positive results have been obtained by using a fractional micro-ablative CO2 laser to treat genital LS. This study aims to assess the safety and efficacy of the fractional micro-ablative CO2 laser in the treatment of penile LS. Five treatments with the fractional CO2 laser were performed on one 69-year-old man affected by penile LS. A significant improvement in symptomatology was noted after the first treatment session. Complete clinical remission was achieved 14 weeks after the last treatment. The fractional micro-ablative CO2 laser may represent a practical therapeutic approach in penile LS.

摘要

外用类固醇仍然是治疗硬化性苔藓(LS)的一线疗法,但在大多数情况下包皮环切术可能治愈该病。使用分次微剥脱二氧化碳激光治疗生殖器LS已取得了积极的效果。本研究旨在评估分次微剥脱二氧化碳激光治疗阴茎LS的安全性和有效性。对一名患有阴茎LS的69岁男性进行了5次二氧化碳激光分次治疗。在第一次治疗后症状有明显改善。最后一次治疗14周后实现了完全临床缓解。分次微剥脱二氧化碳激光可能是治疗阴茎LS的一种实用治疗方法。

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Evidence-based (S3) Guideline on (anogenital) Lichen sclerosus.基于循证医学的(肛门生殖器)硬化性苔藓(S3)指南。
J Eur Acad Dermatol Venereol. 2015 Oct;29(10):e1-43. doi: 10.1111/jdv.13136. Epub 2015 Jul 22.
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Diagnosis and treatment of lichen sclerosus: an update.硬化性苔藓的诊断与治疗:最新进展。
Am J Clin Dermatol. 2013 Feb;14(1):27-47. doi: 10.1007/s40257-012-0006-4.

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