乳糜泻与慢性丙型肝炎病毒感染之间的关联。
Association between Celiac Disease and Chronic Hepatitis C Virus Infection.
作者信息
Garg Ashish, Reddy Chandrasekhar, Duseja Ajay, Chawla Yogesh, Dhiman Radha K
机构信息
Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh.
出版信息
J Clin Exp Hepatol. 2011 Jun;1(1):41-4. doi: 10.1016/S0973-6883(11)60116-3. Epub 2011 Aug 26.
Celiac disease affects the proximal small intestine and is caused by a local immune response to dietary gluten. Celiac disease usually presents with chronic diarrhea; however, presentations with elevated hepatic transaminase levels in blood or with iron-deficiency anemia have been described. Celiac disease has been reported to be associated with autoimmune liver diseases. Hepatitis C virus (HCV) can also initiate autoimmune disease process. Therefore, HCV infection and celiac disease may occur together. Here, we describe 4 cases of celiac disease associated with chronic hepatitis C. This small case series indicates that chronic HCV infection and celiac disease are not causally associated.
乳糜泻累及近端小肠，由对饮食中麸质的局部免疫反应引起。乳糜泻通常表现为慢性腹泻；然而，也有出现血液中肝转氨酶水平升高或缺铁性贫血的病例报道。据报道，乳糜泻与自身免疫性肝病有关。丙型肝炎病毒（HCV）也可引发自身免疫性疾病进程。因此，HCV感染和乳糜泻可能同时发生。在此，我们描述了4例与慢性丙型肝炎相关的乳糜泻病例。这个小病例系列表明，慢性HCV感染与乳糜泻并无因果关系。
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