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格雷夫斯病与原发性胆汁性肝硬化——一种罕见且具有挑战性的关联。

Grave's Disease and Primary Biliary Cirrhosis-An Unusual and Challenging Association.

作者信息

Shetty Shiran, Rajasekaran Senthilkumar, Venkatakrishnan Leela

机构信息

Department of Gastroenterology, PSG IMS & R, Coimbatore, Tamil Nadu 641004, India.

Department of Endocrinology, PSG IMS & R, Coimbatore, Tamil Nadu 641004, India.

出版信息

J Clin Exp Hepatol. 2014 Mar;4(1):66-7. doi: 10.1016/j.jceh.2013.08.001. Epub 2013 Aug 29.

Abstract

Jaundice in Grave's diseases is uncommon, but when it does occur, complication of thyrotoxicosis (heart failure/infection) or intrinsic liver disease should be considered. Grave's disease can cause asymptomatic elevation of liver enzymes, jaundice and rarely acute liver failure. It is associated with other autoimmune diseases like autoimmune hepatitis, or primary biliary cirrhosis. The cause of jaundice in Grave's disease is multifactorial.

摘要

格雷夫斯病(Grave's disease)中的黄疸并不常见,但一旦发生,应考虑甲状腺毒症并发症(心力衰竭/感染)或内在肝脏疾病。格雷夫斯病可导致肝酶无症状升高、黄疸,很少导致急性肝衰竭。它与自身免疫性肝炎或原发性胆汁性肝硬化等其他自身免疫性疾病有关。格雷夫斯病中黄疸的病因是多因素的。

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