Sato Takuro, Kumagai Ichiro, Suzuki Kazuyuki, Kakisaka Keisuke, Abe Koichi
Gastroenterology, Morioka Municipal Hospital, Morioka, JPN.
Gastroenterology and Hepatology, Iwate Medical University, Yahaba-cho, JPN.
Cureus. 2022 Dec 25;14(12):e32941. doi: 10.7759/cureus.32941. eCollection 2022 Dec.
We present a rare case of a 50-year-old woman with simultaneous primary biliary cholangitis (PBC) and autoimmune hyperthyroidism in which the factors associated with liver dysfunction were evaluated over a 3-year follow-up period. Although serum thyroid hormone levels improved after the administration of thiamazole, thyroid dysfunction was not directly associated with liver dysfunction. During the follow-up period, anti-hyperlipidemic drug therapy and eradication therapy for () infection caused transient elevation of serum transaminase levels. It should be recognized that serum liver enzyme levels might be affected by various factors, including the therapies for the many complications of PBC.
我们报告了一例罕见病例，一名50岁女性同时患有原发性胆汁性胆管炎（PBC）和自身免疫性甲状腺功能亢进，在3年的随访期内对与肝功能障碍相关的因素进行了评估。尽管服用甲巯咪唑后血清甲状腺激素水平有所改善，但甲状腺功能障碍与肝功能障碍并无直接关联。在随访期间，抗高脂血症药物治疗以及针对（）感染的根除治疗导致血清转氨酶水平短暂升高。应该认识到，血清肝酶水平可能受到多种因素的影响，包括针对PBC诸多并发症的治疗。
