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头皮交界痣恶变(黑色素瘤)转移至腮腺淋巴结区、颈部淋巴结及背部:一例报告并文献复习

Scalp junctional nevus with malignant transformation (melanoma) metastatic to parotid lymph node region, cervical lymph nodes and the back: a case report and review of literature.

作者信息

Liang Zhuo-Ping, Xu Sheng-En, Jiang Liang, Zhao Chong, Sun Xiao-Qiang, Qin Gang

机构信息

Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Luzhou Medical College Luzhou, Sichuan Province, China.

出版信息

Int J Clin Exp Pathol. 2015 Jan 1;8(1):954-9. eCollection 2015.

Abstract

Parotid malignancy may occur as a primary neoplasm of the salivary tissue or as metastatic involvement of the parotid lymph nodes. Primary tumors of squamous cell carcinoma and malignant melanoma involving the skin of the head and neck have the potential to spread to lymph nodes of the parotid gland. Metastatic malignant melanoma to the back was exceptionally rare and no such reports have been noted in the literature. We reported an exceptional case of intraparotid lymph nodes metastasis of the right scalp junctional nevus with malignant transformation to malignant melanoma in a 48-year-old man. The patient presented with a mass in the parotid gland area, which was misdiagnosed as a primary parotid tumor and surgical removal was performed. Unfortunately, recurrence with newly developed metastatic lesions in the back and cervical lymph nodes occurred 1 year after initial surgical management. This case is presented highlighting the unusual features of metastatic junctional nevus with malignant transformation to malignant melanoma of intraparotid lymph nodes, cervical lymph nodes and the back, which should help us to reduce misdiagnosis and obtain the best results.

摘要

腮腺恶性肿瘤可能作为唾液腺组织的原发性肿瘤出现,也可能是腮腺淋巴结的转移性受累。涉及头颈部皮肤的鳞状细胞癌和恶性黑色素瘤原发性肿瘤有可能扩散至腮腺淋巴结。背部转移性恶性黑色素瘤极为罕见,文献中尚无此类报道。我们报告了一例48岁男性右头皮交界痣发生腮腺内淋巴结转移并恶变成为恶性黑色素瘤的罕见病例。患者腮腺区出现肿块,最初被误诊为原发性腮腺肿瘤并接受了手术切除。不幸的是,在初次手术治疗1年后,背部和颈部淋巴结出现了新的转移性病变并复发。本文展示该病例以突出腮腺内淋巴结、颈部淋巴结及背部交界痣转移并恶变成为恶性黑色素瘤的不寻常特征,这应有助于我们减少误诊并取得最佳治疗效果。

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本文引用的文献

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Primary malignant melanoma of the esophagus: a case report.食管原发性恶性黑色素瘤 1 例报告。
World J Gastroenterol. 2011 Nov 14;17(42):4734-8. doi: 10.3748/wjg.v17.i42.4734.
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Primitive malignant melanoma of the parotid gland.
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