使用富含血小板纤维蛋白膜的羟基磷灰石颗粒治疗重度骨内牙周缺损的牙周组织再生——病例报告
Periodontal regeneration in deep intrabony periodontal defect using hydroxyapatite particles with platelet rich fibrin membrane-a case report.
作者信息
Rastogi Pavitra, Saini Himani, Singhal Rameshwari, Dixit Jaya
机构信息
Assistant Professor, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
Postgraduate Student, Department of Periodontics, Faculty of Dental Sciences, Chhatrapati Shahuji Maharaj Medical University (Erstwhile King George Medical College), Lucknow, India.
出版信息
J Oral Biol Craniofac Res. 2011 Oct-Dec;1(1):41-3. doi: 10.1016/S2212-4268(11)60010-9.
BACKGROUND
Growth factors such as platelet-derived growth factors exert potent effect on wound healing including the regeneration of periodontium. Platelet-rich fibrin (PRF) membrane provides a concentrate of such growth factors, accelerating the wound healing process.
MATERIALS AND METHODS
In this case report, regeneration of the deep periodontal intrabony defect was attempted using hydroxyapatite particles mixed in the PRF membrane to assess if regeneration of new bone is possible.
RESULTS AND CONCLUSION
This resulted in a rapid and complete healing with the decrease in the pocket depth and a gain in the clinical attachment level. Rapid regeneration of the periodontium can be achieved with bone substitutes by incorporating the various growth factors from autogenous blood.
背景
血小板衍生生长因子等生长因子对伤口愈合包括牙周组织再生具有强大作用。富血小板纤维蛋白（PRF）膜可提供此类生长因子的浓缩物，加速伤口愈合过程。
材料与方法
在本病例报告中，尝试使用混入PRF膜中的羟基磷灰石颗粒来促进深部牙周骨内缺损的再生，以评估新骨再生是否可行。
结果与结论
这导致了快速且完全的愈合，牙周袋深度减小，临床附着水平增加。通过结合来自自体血液的各种生长因子，使用骨替代物可实现牙周组织的快速再生。
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