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缺铁和缺铁性贫血是全球性的健康问题。

[Iron deficiency and iron deficiency anemia are global health problems].

作者信息

Dahlerup Jens, Lindgren Stefan, Moum Björn

机构信息

Aarhus Universitetshospital - Medicinsk hepatologisk och gastroenterologisk avdelning V Aarhus, Denmark Aarhus Universitetshospital - Medicinsk hepatologisk och gastroenterologisk avdelning V Aarhus, Denmark.

Lund University - Clinical Sciences, Malmö Malmö, Sweden Lund University - Clinical Sciences, Malmö Malmö, Sweden.

出版信息

Lakartidningen. 2015 Mar 10;112:DAAE.

Abstract

Iron deficiency and iron deficiency anemia are global health problems leading to deterioration in patients' quality of life and more serious prognosis in patients with chronic diseases. The cause of iron deficiency and anemia is usually a combination of increased loss and decreased intestinal absorption and delivery from iron stores due to inflammation. Oral iron is first line treatment, but often hampered by intolerance. Intravenous iron is safe, and the preferred treatment in patients with chronic inflammation and bowel diseases. The goal of treatment is normalisation of hemoglobin concentration and recovery of iron stores. It is important to follow up treatment to ensure that these objectives are met and also long-term in patients with chronic iron loss and/or inflammation to avoid recurrence of anemia.

摘要

缺铁和缺铁性贫血是全球性的健康问题,会导致患者生活质量下降,并且在慢性病患者中预后更严重。缺铁和贫血的原因通常是由于炎症导致铁流失增加、肠道吸收减少以及铁储备的输送减少共同作用的结果。口服铁剂是一线治疗方法,但常因不耐受而受阻。静脉铁剂是安全的,是慢性炎症和肠道疾病患者的首选治疗方法。治疗的目标是使血红蛋白浓度正常化并恢复铁储备。对治疗进行随访很重要,以确保实现这些目标,对于慢性铁流失和/或炎症患者还要进行长期随访,以避免贫血复发。

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