Weaver Meaghann S, Howard Scott C, Lam Catherine G
St Jude Children's Research Hospital, Memphis, TN.
J Pediatr Hematol Oncol. 2015 May;37(4):252-6. doi: 10.1097/MPH.0000000000000319.
Cancer management requires accurate identification of the causes of treatment failure followed by cause-specific interventions. One cause of treatment failure that has received too little attention is abandonment of treatment. Abandonment includes 2 key elements: (1) failing to complete therapy for a disease that could be cured or definitively controlled, and (2) missing all treatment for a sustained time period to an extent that impacts the ability to cure or definitively control the disease. In this Historical Insight paper, we analyze historic and current terminology used to describe treatment abandonment in patients and provide a framework to distinguish it from nonadherence and loss to follow-up.
癌症管理需要准确识别治疗失败的原因，然后采取针对具体原因的干预措施。一个受到关注过少的治疗失败原因是放弃治疗。放弃治疗包括两个关键要素：（1）未能完成对可治愈或可明确控制的疾病的治疗，以及（2）在一段持续时间内完全错过治疗，以至于影响治愈或明确控制该疾病的能力。在这篇历史洞察文章中，我们分析了用于描述患者治疗放弃的历史和当前术语，并提供了一个框架，以将其与不依从和失访区分开来。
