Hu Bao, Miller William H, Neumann Kiel D, Linstad Ethan J, DiMagno Stephen G
Department of Chemistry and Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, NE 68588-0304 (USA); Institute of Industrial Catalysis, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014 (China).
Chemistry. 2015 Apr 20;21(17):6394-8. doi: 10.1002/chem.201500151. Epub 2015 Mar 10.
Iodoarenes are important synthons for a wide range of organic transformations. Here we report a general strategy to prepare singly iodinated electron-rich aromatic compounds through the intermediacy of diaryliodonium salts. This process, which incorporates a phase separation that greatly simplifies product purification, is an attractive replacement for the Sandmeyer approach to iodoarenes that are otherwise difficult to access.
碘代芳烃是广泛有机转化反应中的重要合成子。在此，我们报道了一种通过二芳基碘鎓盐中间体来制备单碘化富电子芳香族化合物的通用策略。该过程包含相分离，极大地简化了产物纯化，是难以通过桑德迈尔方法获得的碘代芳烃的一种有吸引力的替代方法。
