Amato Juliana Neide, Tuon Rogério Antônio, Castelo Paula Midori, Gavião Maria Beatriz Duarte, Barbosa Taís de Souza
Piracicaba Dental School - State University of Campinas, São Paulo, Brazil.
Piracicaba Dental School - State University of Campinas, São Paulo, Brazil; Municipal Government of Piracicaba, São Paulo, Brazil.
Arch Oral Biol. 2015 May;60(5):698-705. doi: 10.1016/j.archoralbio.2015.02.011. Epub 2015 Feb 20.
To evaluate the sleep bruxism, malocclusions, orofacial dysfunctions and salivary levels of cortisol and alpha-amylase in asthmatic children.
108 7-9-yr-old children were selected from Policlinic Santa Teresinha Doutor Antonio Haddad Dib (asthmatics, n=53) and from public schools (controls, n=55), Piracicaba, SP, Brazil. Sleep bruxism diagnosis was confirmed by parental report of grinding sounds and the presence of shiny and polish facets on incisors and/or first permanent molars. The index of orthodontic treatment need was used for occlusion evaluation. Orofacial dysfunctions were evaluated using the nordic orofacial test-screening (NOT-S). Salivary cortisol and alpha-amylase were expressed as "awakening response" (AR), calculated as the difference between levels immediately after awakening and 30 min after waking, and "diurnal decline" (DD), calculated as the difference between levels at 30 min after waking and at bedtime. Data were analyzed using Shapiro-Wilk/Kolmogorov-Smirnov, Chi-square, unpaired t test/Mann-Whitney and paired t/Wilcoxon tests.
Sleep bruxism was more prevalent in children with asthma than controls (47.2% vs. 27.3%, p<0.05). Asthmatics had higher scores of NOT-S total and interview (p<0.05). Dysfunctions on sensory function and chewing and swallowing were more frequent in asthmatics (p<0.05). Salivary cortisol AR on weekend was significantly higher for asthmatics (p<0.05). Salivary cortisol DD was significantly higher on weekday than weekend for controls (p<0.05). There were no significant differences in alpha-amylase values in and between groups.
The presence of asthma in children was associated with sleep bruxism, negative perception of sensory, chewing and swallowing functions, and higher concentrations of salivary cortisol on weekend.
评估哮喘儿童的睡眠磨牙症、错牙合畸形、口面部功能障碍以及唾液中皮质醇和α-淀粉酶的水平。
从巴西圣保罗州皮拉西卡巴市的圣特雷西尼亚·多托·安东尼奥·哈达德·迪布综合诊所（哮喘患儿，n = 53）和公立学校（对照组，n = 55）选取108名7至9岁儿童。通过家长报告的磨牙声音以及门牙和/或第一恒磨牙上存在发亮和抛光面来确诊睡眠磨牙症。使用正畸治疗需求指数评估咬合情况。采用北欧口面部测试筛查（NOT-S）评估口面部功能障碍。唾液皮质醇和α-淀粉酶以“觉醒反应”（AR）表示，计算为觉醒后即刻水平与醒来30分钟后水平之差，以及“日间下降”（DD），计算为醒来30分钟后水平与就寝时间水平之差。数据采用Shapiro-Wilk/Kolmogorov-Smirnov检验、卡方检验、非配对t检验/Mann-Whitney检验以及配对t检验/Wilcoxon检验进行分析。
哮喘儿童的睡眠磨牙症比对照组更普遍（47.2%对27.3%，p<0.05）。哮喘患儿的NOT-S总分和访谈得分更高（p<0.05）。哮喘患儿的感觉功能以及咀嚼和吞咽功能障碍更常见（p<0.05）。哮喘患儿周末的唾液皮质醇AR显著更高（p<0.05）。对照组工作日的唾液皮质醇DD显著高于周末（p<0.05）。各组内及组间α-淀粉酶值无显著差异。
儿童哮喘的存在与睡眠磨牙症、对感觉、咀嚼和吞咽功能的负面认知以及周末唾液皮质醇浓度升高有关。
