Aguayo Victor M, Aneja Satinder, Badgaiyan Nina, Singh Karanveer
1United Nations Children's Fund (UNICEF),Regional Office for South Asia,PO Box 5815,Lekhnath Marg,Kathmandu,Nepal.
2Department of Pediatrics,Lady Hardinge Medical College,New Delhi,India.
Public Health Nutr. 2015 Dec;18(17):3244-8. doi: 10.1017/S1368980015000543. Epub 2015 Mar 11.
To assess the appropriateness of current mid upper-arm circumference (MUAC) cut-offs to identify children with severe acute malnutrition in India.
The analysis concerned 6307 children admitted to nutrition rehabilitation centres (2009-2011) where they received therapeutic care as per guidelines by WHO and the Indian Academy of Pediatrics.
States of Jharkhand, Madhya Pradesh and Uttar Pradesh, India.
Children aged 6-59 months with bilateral pitting oedema or weight-for-height Z-score (WHZ)<-3 or MUAC<115 mm at admission.
Children aged 6-23 months represented ~80 % of the admissions. Among them, the proportion with WHZ<-3 was similar to that with MUAC<115 mm (85·7 % v. 81·8 %); the proportion with MUAC<115 mm whose WHZ was <-3 was 82·6 %; and the proportion with WHZ<-3 whose MUAC<115 mm was 78·8 %. MUAC<115 mm was as effective as WHZ<-3 in identifying 6-59-month-old children with medical complications (32·2 % v. 31·6 %, respectively), the most important risk factor of death among oedema-free children. Furthermore, death rates in children with MUAC<115 mm were higher than in children with WHZ<-3 (0·61 % v. 0·58 %, respectively) and 91 % of the deaths among oedema-free children were deaths of children with MUAC<115 mm.
In populations similar to those included in our analysis, MUAC<115 mm appears to be an appropriate criterion to identify children with severe acute malnutrition who are at a greater risk of medical complications and death, particularly among children 6-23 months old.
评估当前上臂中部周长(MUAC)界值用于识别印度重度急性营养不良儿童的适宜性。
该分析涉及6307名入住营养康复中心的儿童(2009 - 2011年),他们在中心按照世界卫生组织和印度儿科学会的指南接受治疗护理。
印度恰尔肯德邦、中央邦和北方邦。
入院时患有双侧凹陷性水肿或身高别体重Z评分(WHZ)<-3或MUAC<115毫米的6 - 59月龄儿童。
6 - 23月龄儿童约占入院儿童的80%。其中,WHZ<-3的儿童比例与MUAC<115毫米的儿童比例相似(85.7%对81.8%);MUAC<115毫米且WHZ<-3的儿童比例为82.6%;WHZ<-3且MUAC<115毫米的儿童比例为78.8%。MUAC<115毫米在识别有医学并发症的6 - 59月龄儿童方面与WHZ<-3同样有效(分别为32.2%和31.6%),这是无水肿儿童中最重要的死亡风险因素。此外,MUAC<115毫米儿童的死亡率高于WHZ<-3的儿童(分别为0.61%和0.58%),无水肿儿童中91%的死亡是MUAC<115毫米儿童的死亡。
在与我们分析中纳入的人群相似的群体中,MUAC<115毫米似乎是识别有更高医学并发症和死亡风险的重度急性营养不良儿童的适宜标准,尤其是在6 - 23月龄儿童中。