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富含豆类饮食对糖尿病高危个体心血管代谢危险因素的影响:一项交叉研究。

Effects of Legume-Enriched Diet on Cardiometabolic Risk Factors among Individuals at Risk for Diabetes: A Crossover Study.

作者信息

Saraf-Bank Sahar, Esmaillzadeh Ahmad, Faghihimani Elham, Azadbakht Leila

机构信息

a Food Security Research Center, Isfahan University of Medical Sciences , Isfahan , IRAN.

b Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences , Isfahan , IRAN.

出版信息

J Am Coll Nutr. 2016;35(1):31-40. doi: 10.1080/07315724.2014.931262. Epub 2015 Mar 11.

Abstract

AIMS

First-degree relatives of patients with diabetes are at high risk for chronic diseases, including type 2 diabetes and obesity. Our purpose was to determine the effects of consuming 4 servings of legumes per week on lipid profiles, glycemic indices, and blood pressure of participants with family history of diabetes over 6 weeks of intervention.

METHODS

A total of 26 first-degree relatives of patients with diabetes (14 women and 12 men) participated in this randomized crossover clinical trial study. Participants were randomly assigned to a legume-enriched diet or habitual diet for 6 weeks. Paired t test and repeated measures analysis of variance were used to compare data for the 2 experimental diets.

RESULTS

The mean ± SE of legumes intake during the legume phase was 111.12 ± 10.53 g/day that was significantly higher (p < 0.001) than the amounts of legumes during habitual diet (50.73 ± 7.10 g/d). Percentage changes for cardiovascular disease risk factors did not change significantly following 6 weeks of legume consumption.

CONCLUSIONS

Consumption of 4 servings of legumes per week had no significant effect on anthropometric measurements, glycemic indices, and lipid profiles of participants with family history of diabetes, though it could reduce systolic and diastolic blood pressure at a marginally significant level.

摘要

目的

糖尿病患者的一级亲属患包括2型糖尿病和肥胖症在内的慢性病风险很高。我们的目的是确定在为期6周的干预中,每周食用4份豆类对有糖尿病家族史的参与者的血脂谱、血糖指数和血压的影响。

方法

共有26名糖尿病患者的一级亲属(14名女性和12名男性)参与了这项随机交叉临床试验研究。参与者被随机分配到富含豆类的饮食组或常规饮食组,为期6周。采用配对t检验和重复测量方差分析来比较两种实验饮食的数据。

结果

豆类饮食阶段豆类的平均摄入量±标准误为111.12±10.53克/天,显著高于常规饮食期间的豆类摄入量(50.73±7.10克/天,p<0.001)。食用豆类6周后,心血管疾病危险因素的百分比变化没有显著改变。

结论

每周食用4份豆类对有糖尿病家族史的参与者的人体测量指标、血糖指数和血脂谱没有显著影响,尽管它能在边缘显著水平上降低收缩压和舒张压。

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