Thakur Anita, Gupta Bhupender, Gupta Anmol, Chauhan Raman
Assistant Professor, Department of Community Medicine, Indira Gandhi Medical College (IGMC), Shimla, Himachal Pradesh, India.
Indian J Public Health. 2015 Jan-Mar;59(1):45-8. doi: 10.4103/0019-557X.152862.
In Himachal Pradesh, cancer cervix is a major public health problem since it ranks as the number one female cancer. A case-control study of 226 newly diagnosed, histopathologically confirmed cases of cancer cervix and equal number of matched controls was conducted at Regional Cancer Center, Himachal Pradesh during the period from July 2008 to October 2009 with the objective to study the common factors associated with cancer cervix. Univariate analysis identified 10 risk factors associated significantly with the disease. On multiple logistic regression, however, only seven risk factors were found to be associated significantly with the disease. These were: Age at birth of first child, spacing between two children, age at marriage, literacy, socioeconomic status, multiparity, and poor genital hygiene. Risk factors such as poor genital hygiene, age at birth of first child <19 years, early marriage, illiteracy, multiparity, and low socioeconomic status were highly prevalent in the study subjects and were found to be significantly associated with cancer cervix.
在喜马偕尔邦，宫颈癌是一个重大的公共卫生问题，因为它是排名第一的女性癌症。2008年7月至2009年10月期间，在喜马偕尔邦地区癌症中心对226例新诊断的、经组织病理学确诊的宫颈癌病例以及数量相等的匹配对照进行了一项病例对照研究，目的是研究与宫颈癌相关的常见因素。单因素分析确定了10个与该疾病显著相关的风险因素。然而，在多因素逻辑回归分析中，仅发现7个风险因素与该疾病显著相关。这些因素包括：第一个孩子出生时的年龄、两个孩子之间的间隔、结婚年龄、识字率、社会经济地位、多产以及不良的生殖器官卫生状况。不良的生殖器官卫生状况、第一个孩子出生时年龄<19岁、早婚、文盲、多产以及低社会经济地位等风险因素在研究对象中非常普遍，并且被发现与宫颈癌显著相关。
