Division of Endocrinology and Metabolic Disorders, Department of Internal Medicine, Turgut Özal University Faculty of Medicine, Ankara, Turkey.
Department of Internal Medicine, Kırıkkale University Faculty of Medicine, Kırıkkale, Turkey.
Balkan Med J. 2015 Jan;32(1):124-6. doi: 10.5152/balkanmedj.2015.15123. Epub 2015 Jan 1.
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus and can lead to death if untreated. It is a complex metabolic state characterised by hyperglycaemia, acidosis and ketonuria. Bonsai is one of the herbal incense products that contains synthetic cannabinoid and can be easily accessible via the internet in many countries. It cannot be detected in blood and urine studies using conventional methods. Synthetic cannabinoid abuse is associated with severe side effects, including tachycardia, high blood pressure, acidosis, excess sedation and coma.
A 17-year-old male patient was brought to the emergency department with sudden onset of dyspnoea. Laboratory investigations revealed hyperglycaemia, acidosis and ketonuria. He was admitted to the intensive care unit with a diagnosis of diabetic ketoacidosis. He was not considered a typical case of diabetic ketoacidosis because of the tendency to hypokalaemia, persistent tachycardia and bronchoscopic findings. We learned from his friends that he had used cannabis for a week and used bonzai on the day that he was brought to the emergency service.
Diabetic ketoacidosis with prolonged acidosis and tendency to hypokalaemia are investigated for the consumption of synthetic cannabinoids.
糖尿病酮症酸中毒（DKA）是糖尿病一种潜在的危及生命的并发症，如果不治疗，可能导致死亡。它是一种以高血糖、酸中毒和酮尿为特征的复杂代谢状态。博彩是一种含有合成大麻素的草药熏香产品，在许多国家可以通过互联网轻松获得。它不能通过常规方法在血液和尿液研究中检测到。合成大麻素滥用与严重的副作用有关，包括心动过速、高血压、酸中毒、过度镇静和昏迷。
一名 17 岁男性患者因突然出现呼吸困难被送往急诊部。实验室检查显示高血糖、酸中毒和酮尿。他因糖尿病酮症酸中毒被收入重症监护病房。由于低钾血症、持续心动过速和支气管镜检查的倾向，他不被认为是典型的糖尿病酮症酸中毒病例。我们从他的朋友那里了解到，他在一周前使用了大麻，并在被送往急诊室的那天使用了博彩。
对于酸中毒持续时间长和低钾血症倾向的糖尿病酮症酸中毒，应调查合成大麻素的摄入情况。
