再现性舌震颤：帕金森病的首发症状
Re-emergent Tongue Tremor as the Presenting Symptom of Parkinson's Disease.
机构信息
Department of Neurology, Cerrahpaşa Faculty of Medicine, İstanbul University, İstanbul, Turkey.
出版信息
Balkan Med J. 2015 Jan;32(1):127-8. doi: 10.5152/balkanmedj.2015.15008. Epub 2015 Jan 1.
BACKGROUND
The most common symptom of Parkinson's disease is the unilateral, typically resting tremor in body parts, most commonly in the upper extremities. However, this finding can spread to the other parts of the body like lips, chin, jaw and tongue during the course of the disease. Nevertheless, we have not come across any Parkinson's disease case presenting with tongue tremor in the literature.
CASE REPORT
Here, we present a 58 year-old man with Parkinson's disease presenting with tongue tremor, his striking response to the levodopa test and his follow-up data.
CONCLUSION
The topography of motor symptoms at onset in Parkinson's disease is presumably determined by the severity of the Lewy body neuronal degeneration in distinct parts of the substantia nigra. Therefore, patterns of somatic symptom progression in Parkinson's disease indicate that involvement of the cranial structures always follows the development of symptoms in the extremities. However, in our case, cranial structures seem to precede the involvement of extremity-related areas.
背景
帕金森病最常见的症状是单侧、通常在休息时出现的身体部位震颤，最常见于上肢。然而，随着疾病的发展，这种震颤可能会扩散到嘴唇、下巴、下颚和舌头等其他身体部位。然而，我们在文献中尚未发现任何以舌震颤为表现的帕金森病病例。
病例报告
在这里，我们介绍了一位 58 岁的男性帕金森病患者，他表现为舌震颤，对左旋多巴测试有明显反应，以及他的随访数据。
结论
帕金森病运动症状在发病时的分布，推测是由黑质中不同部位路易体神经元变性的严重程度决定的。因此，帕金森病躯体症状的进展模式表明，颅结构的受累总是紧随四肢症状的发展。然而，在我们的病例中，颅结构似乎先于与四肢相关区域的受累。
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