颈部淋巴结、甲状腺炎和眼病：免疫球蛋白 G4 相关疾病的多形性表现。
Cervical lymph nodes, thyroiditis and ophthalmopathy: the pleomorphic face of an immunoglobulin g4-related disease.
机构信息
Department of Endocrinology, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Department of Pathology, Université Libre de Bruxelles, Brussels, Belgium.
出版信息
Eur Thyroid J. 2014 Dec;3(4):252-7. doi: 10.1159/000369204. Epub 2014 Nov 29.
Abstract
We report a case of immunoglobulin G4-related disease (IgG4-RD) presenting with a clinical course suggestive of fibrosing thyroiditis and endocrine ophthalmopathy associated with enlarged cervical lymph nodes. This clinical presentation should prompt a search for associated systemic disorders, including an IgG4-RD. The clue to the exact diagnosis of the underlying disease is histological examination showing an IgG4 plasmatocytic infiltrate in the inflammatory organs involved.
摘要
我们报告了一例免疫球蛋白 G4 相关疾病（IgG4-RD），其临床表现提示纤维性甲状腺炎和内分泌性眼病，伴有颈淋巴结肿大。这种临床表现应提示寻找相关的系统性疾病，包括 IgG4-RD。明确诊断基础疾病的线索是组织学检查显示受累炎症器官中有 IgG4 浆细胞浸润。
相似文献
1
Cervical lymph nodes, thyroiditis and ophthalmopathy: the pleomorphic face of an immunoglobulin g4-related disease.颈部淋巴结、甲状腺炎和眼病：免疫球蛋白 G4 相关疾病的多形性表现。
Eur Thyroid J. 2014 Dec;3(4):252-7. doi: 10.1159/000369204. Epub 2014 Nov 29.
2
Exophthalmos in a young woman with no graves' disease - a case report of IgG4-related orbitopathy.一名无格雷夫斯病的年轻女性出现眼球突出——IgG4相关性眼眶病病例报告
BMC Ophthalmol. 2018 Jan 12;18(1):5. doi: 10.1186/s12886-018-0672-y.
3
Visual impairment in immunoglobulin G4-related disease: A case report.免疫球蛋白G4相关疾病中的视力损害：一例报告。
Exp Ther Med. 2021 Mar;21(3):200. doi: 10.3892/etm.2021.9633. Epub 2021 Jan 11.
4
DIAGNOSIS OF ENDOCRINE DISEASE: IgG4-related thyroid autoimmune disease.内分泌疾病诊断：IgG4 相关甲状腺自身免疫性疾病。
Eur J Endocrinol. 2019 May 1;180(5):R175-R183. doi: 10.1530/EJE-18-1024.
5
Immunoglobulin G4-Related Thyroid Diseases.免疫球蛋白G4相关性甲状腺疾病
Eur Thyroid J. 2016 Dec;5(4):231-239. doi: 10.1159/000452623. Epub 2016 Dec 3.
6
Immunoglobulin G4 related thyroid disorders: Diagnostic challenges and clinical outcomes.免疫球蛋白G4相关甲状腺疾病：诊断挑战与临床结局
Endokrynol Pol. 2016;67(5):520-524. doi: 10.5603/EP.2016.0061.
7
Clinical Implications of Immunoglobulin G4 to Graves' Ophthalmopathy.免疫球蛋白 G4 与格雷夫斯眼病的临床意义。
Thyroid. 2017 Sep;27(9):1185-1193. doi: 10.1089/thy.2017.0126.
8
Serum immunoglobulin G4 levels and Graves' disease phenotype.血清免疫球蛋白G4水平与格雷夫斯病表型
Endocrine. 2017 Feb;55(2):478-484. doi: 10.1007/s12020-016-1157-5. Epub 2016 Nov 7.
9
Distribution of serum immunoglobulin G4 levels in Hashimoto's thyroiditis and clinical features of Hashimoto's thyroiditis with elevated serum immunoglobulin G4 levels.桥本甲状腺炎患者血清免疫球蛋白G4水平分布及血清免疫球蛋白G4水平升高的桥本甲状腺炎的临床特征
Endocr J. 2015;62(8):711-7. doi: 10.1507/endocrj.EJ15-0157. Epub 2015 May 20.
10
IgG4 thyroiditis in the Asian population.亚洲人群中的IgG4相关性甲状腺炎
Gland Surg. 2020 Oct;9(5):1838-1846. doi: 10.21037/gs-20-417.
本文引用的文献
1
Clinical features of a new disease concept, IgG4-related thyroiditis.一种新疾病概念 IgG4 相关甲状腺炎的临床特征。
Scand J Rheumatol. 2013;42(4):325-30. doi: 10.3109/03009742.2012.761281. Epub 2013 Mar 16.
2
Fibrosing variant of Hashimoto thyroiditis is an IgG4 related disease.纤维型桥本甲状腺炎是一种 IgG4 相关疾病。
J Clin Pathol. 2012 Aug;65(8):725-8. doi: 10.1136/jclinpath-2011-200485. Epub 2012 Jun 1.
3
IgG4-related disease.IgG4相关性疾病
N Engl J Med. 2012 Feb 9;366(6):539-51. doi: 10.1056/NEJMra1104650.
4
Graves'-like orbitopathy in a patient with chronic autoimmune pancreatitis.慢性自身免疫性胰腺炎患者的 Graves 样眼病。
Thyroid. 2011 Dec;21(12):1389-92. doi: 10.1089/thy.2011.0191. Epub 2011 Nov 8.
5
Clinical review: Riedel's thyroiditis: a clinical review.临床综述：雷德尔甲状腺炎：临床综述。
J Clin Endocrinol Metab. 2011 Oct;96(10):3031-41. doi: 10.1210/jc.2011-0617. Epub 2011 Aug 10.
6
Unicentric mixed variant Castleman disease associated with Hashimoto disease: the role of PET/CT in staging and evaluating response to the treatment.单发中心性混合细胞型 Castleman 病合并桥本甲状腺炎：PET/CT 在分期及评估治疗反应中的作用。
Cancer Imaging. 2011 Jun 15;11(1):52-5. doi: 10.1102/1470-7330.2011.0011.
7
IgG4-related disease: a novel lymphoproliferative disorder discovered and established in Japan in the 21st century.IgG4相关性疾病：21世纪在日本发现并确立的一种新型淋巴增殖性疾病。
J Clin Exp Hematop. 2011;51(1):13-20. doi: 10.3960/jslrt.51.13.
8
Numerous IgG4-positive plasma cells are ubiquitous in diverse localised non-specific chronic inflammatory conditions and need to be distinguished from IgG4-related systemic disorders.在各种局部非特异性慢性炎症性疾病中普遍存在大量 IgG4 阳性浆细胞，需要将其与 IgG4 相关的系统性疾病区分开来。
J Clin Pathol. 2011 Mar;64(3):237-43. doi: 10.1136/jcp.2010.085613. Epub 2011 Jan 12.
9
Deposition of complement C3c, immunoglobulin (Ig)G4 and IgG at the basement membrane of pancreatic ducts and acini in autoimmune pancreatitis.自身免疫性胰腺炎中胰管和腺泡的基底膜沉积补体 C3c、免疫球蛋白 (Ig)G4 和 IgG。
Histopathology. 2010 Dec;57(6):825-35. doi: 10.1111/j.1365-2559.2010.03717.x.
10
Clinical characterization and immunopathologic features of sclerosing dacryoadenitis and riedel thyroiditis.硬化性泪腺炎和Riedel甲状腺炎的临床特征及免疫病理特征
Arch Ophthalmol. 2010 Dec;128(12):1626-8. doi: 10.1001/archophthalmol.2010.299.
Zotero 插件