Department of Endocrinology, Universitair Ziekenhuis Brussel, Brussels, Belgium.
Department of Pathology, Université Libre de Bruxelles, Brussels, Belgium.
Eur Thyroid J. 2014 Dec;3(4):252-7. doi: 10.1159/000369204. Epub 2014 Nov 29.
We report a case of immunoglobulin G4-related disease (IgG4-RD) presenting with a clinical course suggestive of fibrosing thyroiditis and endocrine ophthalmopathy associated with enlarged cervical lymph nodes. This clinical presentation should prompt a search for associated systemic disorders, including an IgG4-RD. The clue to the exact diagnosis of the underlying disease is histological examination showing an IgG4 plasmatocytic infiltrate in the inflammatory organs involved.
我们报告了一例免疫球蛋白 G4 相关疾病（IgG4-RD），其临床表现提示纤维性甲状腺炎和内分泌性眼病，伴有颈淋巴结肿大。这种临床表现应提示寻找相关的系统性疾病，包括 IgG4-RD。明确诊断基础疾病的线索是组织学检查显示受累炎症器官中有 IgG4 浆细胞浸润。
