Mooiweer Ronald, Sbrizzi Alessandro, El Aidi Hamza, Eikendal Anouk L M, Raaijmakers Alexander, Visser Fredy, van den Berg Cornelis A T, Leiner Tim, Luijten Peter R, Hoogduin Hans
Department of Radiology, University Medical Center Utrecht, The Netherlands.
Department of Cardiology, University Medical Center Utrecht, The Netherlands.
Magn Reson Med. 2016 Feb;75(2):547-55. doi: 10.1002/mrm.25599. Epub 2015 Mar 11.
Aortic vessel wall imaging requires large coverage and a high spatial resolution, which makes it prohibitively time-consuming for clinical use. This work explores the feasibility of imaging the descending aorta in acceptable scan time, using two-dimensional (2D) spatially selective excitation and a new way of inversion recovery for black blood imaging.
The excitation pattern and field of view in a 3D gradient echo sequence are reduced in two dimensions, following the aorta's anisotropic geometry. Black blood contrast is obtained by partially inverting the blood's magnetization in the heart at the start of the cardiac cycle. Imaging is delayed until the inverted blood has filled the desired part of the aorta. The flip angle and delay are determined such that the blood signal is nulled upon arrival in the aorta.
Experiments on eight volunteers showed that the descending aortic vessel wall could be imaged over more than 15 cm at a maximal resolution of 1.5 × 1.5 × 1.5 mm(3) in less than 5 min minimal scan time.
This feasibility study demonstrates that time-efficient isotropic imaging of the descending aorta is possible by using 2D spatially selective excitation for motion artifact reduction and a new way of inversion recovery for black blood imaging.
主动脉血管壁成像需要大视野覆盖和高空间分辨率,这使得其在临床应用中耗时过长而难以实现。本研究探讨了在可接受的扫描时间内对降主动脉进行成像的可行性,采用二维(2D)空间选择性激发和一种用于黑血成像的新的反转恢复方法。
根据主动脉的各向异性几何形状,在三维梯度回波序列中,将激发模式和视野在两个维度上减小。通过在心动周期开始时部分反转心脏中血液的磁化来获得黑血对比。成像延迟至反转血液充满主动脉的所需部分。确定翻转角和延迟时间,使得血液信号在到达主动脉时被消除。
对8名志愿者的实验表明,在最短扫描时间不到5分钟的情况下,能够以1.5×1.5×1.5毫米(3)的最大分辨率对超过15厘米的降主动脉血管壁进行成像。
这项可行性研究表明,通过使用二维空间选择性激发来减少运动伪影以及采用一种用于黑血成像的新的反转恢复方法,可以实现降主动脉的高效各向同性成像。