College of Engineering, Peking University, Beijing, People's Republic of China.
Magn Reson Med. 2013 Nov;70(5):1347-52. doi: 10.1002/mrm.24579. Epub 2012 Dec 27.
In this study, we sought to investigate the feasibility of turbo fast three-dimensional (3D) black-blood imaging by combining a 3D motion-sensitizing driven equilibrium rapid gradient echo sequence with compressed sensing.
A pseudo-centric phase encoding order was developed for compressed sensing-3D motion-sensitizing driven equilibrium rapid gradient echo to suppress flow signal in undersampled 3D k-space. Nine healthy volunteers were recruited for this study. Signal-to-tissue ratio, contrast-to-tissue ratio (CTR) and CTR efficiency (CTReff ) between fully sampled and undersampled images were calculated and compared in seven subjects. Moreover, isotropic high resolution images using different compressed sensing acceleration factors were evaluated in two other subjects.
Wall-lumen signal-to-tissue ratio or CTR were comparable between the undersampled and the fully sampled images, while significant improvement of CTReff was achieved in the undersampled images. At an isotropic high spatial resolution of 0.7 × 0.7 × 0.7 mm(3) , all undersampled images exhibited similar level of the flow suppression efficiency and the capability of delineating outer vessel wall boundary and lumen-wall interface, when compared with the fully sampled images.
The proposed turbo fast compressed sensing 3D black-blood imaging technique improves scan efficiency without sacrificing flow suppression efficiency and vessel wall image quality. It could be a valuable tool for rapid 3D vessel wall imaging.
本研究旨在探讨结合三维运动敏感驱动平衡快速梯度回波序列和压缩感知技术实现涡轮快速三维（3D）黑血成像的可行性。
为了在欠采样三维 k 空间中抑制血流信号，我们开发了一种用于压缩感知-3D 运动敏感驱动平衡快速梯度回波的伪中心相位编码顺序。本研究招募了 9 名健康志愿者。在 7 名受试者中，计算并比较了完全采样和欠采样图像的信号组织比、对比组织比（CTR）和对比组织效率（CTReff）。另外，在另外 2 名受试者中，我们评估了不同压缩感知加速因子的各向同性高分辨率图像。
壁腔信号组织比或 CTR 在欠采样和完全采样图像之间具有可比性，而在欠采样图像中实现了显著提高的 CTReff。在各向同性高空间分辨率为 0.7×0.7×0.7mm3时，与完全采样图像相比，所有欠采样图像均表现出相似的流抑制效率和外血管壁边界和腔壁界面描绘能力。
所提出的涡轮快速压缩感知 3D 黑血成像技术在不牺牲流抑制效率和血管壁图像质量的情况下提高了扫描效率。它可能是快速 3D 血管壁成像的有价值工具。
