Neuberger James
Organ Donation and Transplantation, NHS Blood and Transplant, Fox Den Road, Bristol, BS34 8RR, UK,
Langenbecks Arch Surg. 2015 Jul;400(5):559-66. doi: 10.1007/s00423-015-1296-9. Epub 2015 Mar 12.
This review aims to outline the delivery of liver transplant services in the UK.
Liver transplantation in the UK is based on seven designated transplant units serving a population of just over 60 million people. Nearly 900 liver transplants were done in 2013/2014.
Potential deceased donors are identified and referred to centrally employed specialist nurses for obtaining family consent and for donor characterisation. Organs are retrieved by a National Organ Retrieval Service, based on seven abdominal and six cardiothoracic retrieval teams providing a 24/7 service which has shown to be capable of retrieving organs from up to ten donors a day. Donated organs are allocated first nationally to those who qualify for super-urgent listing. The next priority is for splitting livers, and if there is no suitable recipient or the liver is not suitable for splitting, then livers are offered first to the local centre; each centre has a designated donor zone, adjusted annually to ensure equity between the number of patients listed and the number of donors. The allocation scheme is being reviewed, and national schemes based on need, utility and benefit are being assessed.
Outcomes are monitored by National Health Service Blood and Transplant (NHSBT), and if there is a possibility of adverse deviation, then further inquiries are made. Outcomes, both from listing and from transplantation, are published by the centre on the NHSBT website ( www.odt.nhs.uk ). NHSBT works closely with stakeholders primarily through the advisory groups with clinicians, patients, lay members and professional societies and aims to provide openness and transparency.
The system for organ donation and delivery of liver transplant in the UK has developed and is now providing an effective and efficient service, but there remains room for improvement.
本综述旨在概述英国肝脏移植服务的提供情况。
英国的肝脏移植基于七个指定的移植单位,服务于略多于6000万人口。2013/2014年进行了近900例肝脏移植。
确定潜在的已故捐赠者,并将其转介给中央雇佣的专科护士,以获得家属同意并对捐赠者进行评估。器官由国家器官获取服务机构获取,该机构基于七个腹部和六个心胸获取团队提供全天候服务,已证明每天能够从多达十名捐赠者身上获取器官。捐赠的器官首先在全国范围内分配给符合超级紧急名单资格的人。下一个优先事项是肝脏分割,如果没有合适的接受者或肝脏不适合分割,那么肝脏首先提供给当地中心;每个中心都有一个指定的捐赠者区域,每年进行调整以确保登记患者数量和捐赠者数量之间的公平性。分配方案正在审查中,基于需求、效用和益处的国家方案正在评估中。
结果由国民健康服务血液与移植机构(NHSBT)监测,如果有可能出现不良偏差,则会进行进一步调查。中心在NHSBT网站(www.odt.nhs.uk)上公布登记和移植的结果。NHSBT主要通过与临床医生、患者、非专业成员和专业协会的咨询小组与利益相关者密切合作,旨在实现公开和透明。
英国的器官捐赠和肝脏移植服务系统已经发展起来,目前正在提供有效且高效的服务,但仍有改进的空间。