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[经皮肝穿刺胆管造影术(PTC)的当前适应证]

[Current indications for percutaneous transhepatic cholangiography (PTC)].

作者信息

Ghilardi G, Bortolani E M, Sgroi G, Pecis C, Stringhi E

出版信息

Minerva Chir. 1989 Dec 31;44(23-24):2383-8.

PMID:2576464
Abstract

Percutaneous transhepatic cholangiography (PTC) showed its widest diffusion during the late '70s while since the early '80s it was gradually replaced by endoscopic retrograde cholangiopancreatography (ERCP). Anyway, a well definite role for PTC still exists. PTC was performed in 60 of 131 cases of obstructive disease of the biliary tree: the indications are illustrated in detail. The statistical indicators utilized to choose this examination were: echographic determination of the diameter of the biliary tree, bilirubinemia, alkaline phosphatase (ALP) and serum gamma-GT. Data collected during this study showed that biliary dilation has a significant correlation to serum levels of ALP, while bilirubin has not. Biliary dilation is currently well established by echography: in some instances, however, biliary obstruction is earlier suggested by elevated serum enzymes of biliary stasis, while it is clearly demonstrated that biliary dilation is a precursor of jaundice, better defined as an expression of biliary hypertension. Based on these observations and on the review of the literature, the Authors believe that PTC still remains a second choice examination as compared to ERCP: when the latter be not effective for diagnosis or decompression of the biliary tree, then PTC can be resolutive.

摘要

经皮肝穿刺胆管造影术(PTC)在20世纪70年代末应用最为广泛,而自20世纪80年代初以来,它逐渐被内镜逆行胰胆管造影术(ERCP)所取代。无论如何,PTC仍有明确的作用。在131例胆道梗阻性疾病患者中,有60例进行了PTC检查,并详细说明了其适应证。用于选择此项检查的统计指标包括:超声测定胆管直径、胆红素血症、碱性磷酸酶(ALP)和血清γ-谷氨酰转肽酶(γ-GT)。本研究收集的数据显示,胆管扩张与血清ALP水平显著相关,而与胆红素无关。目前,超声检查已能很好地确定胆管扩张:然而,在某些情况下,胆汁淤积导致的血清酶升高可更早提示胆道梗阻,同时有明确证据表明胆管扩张是黄疸的先兆,更确切地说是胆道高压的一种表现。基于这些观察结果并结合文献回顾,作者认为与ERCP相比,PTC仍是一种次选检查:当ERCP对胆管树的诊断或减压无效时,PTC可能会有决定性作用。

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