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[羟基苯的2,4-和2,6-二甲基衍生物在温血动物体内分布的具体特征]

[Specific features of the distribution of 2,4- and 2,6-dimethyl derivatives of hydroxybenzene in the body of the warm-blooded animals].

作者信息

Pugacheva O I, Astashkina A P

出版信息

Sud Med Ekspert. 2014 Jul-Aug;57(4):44-8.

Abstract

This study was designed to elucidate the specific features of the distribution of 2,4- and 2,6-dimethyl derivatives of hydroxybenzene in the body of the warm-blooded animals (rats) after the intragastric administration of these poisonous substances. It was shown that large amounts of these compounds are present in the unmetabolized form in the blood and internal organs of the experimental animals. Their largest quantities were found in the stomach contents, spleen, and small intestines.

摘要

本研究旨在阐明在给温血动物(大鼠)经胃内给予这些有毒物质后,羟基苯的2,4 - 和2,6 - 二甲基衍生物在其体内分布的具体特征。结果表明,这些化合物大量以未代谢形式存在于实验动物的血液和内脏器官中。在胃内容物、脾脏和小肠中发现它们的含量最高。

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