Park Kui Young, Hyun Moo Yeol, Jeong Se Yeong, Kim Beom Joon, Kim Myeung Nam, Hong Chang Kwun
Department of Dermatology, Chung-Ang University College of Medicine, Seoul, South Korea.
Dermatology. 2015;230(4):299-301. doi: 10.1159/000368773. Epub 2015 Mar 3.
Persistent erythema and severe rosacea flushing can cause significant physical discomfort and emotional stress to patients. Currently, no satisfactory treatments are available.
We report two cases of refractory flushing and erythema of rosacea that were successfully treated with intradermal botulinum toxin injections.
Good cosmetic results were achieved for both patients. The side effects during and after treatment were mild pain and localized bruising; these symptoms resolved within several days without further treatment.
Intradermal botulinum toxin injection may be an effective treatment for refractory erythema and rosacea flushing that deserves further study in a larger patient population.
持续性红斑和重度酒渣鼻潮红会给患者带来极大的身体不适和情绪压力。目前尚无令人满意的治疗方法。
我们报告了两例难治性酒渣鼻潮红和红斑患者，通过皮内注射肉毒杆菌毒素成功治愈。
两名患者均取得了良好的美容效果。治疗期间及之后的副作用为轻微疼痛和局部瘀斑；这些症状在数天内自行缓解，无需进一步治疗。
皮内注射肉毒杆菌毒素可能是治疗难治性红斑和酒渣鼻潮红的有效方法，值得在更多患者中进一步研究。
