Department of Dermatology, University Hospital of Aalborg, Aalborg, Denmark.
Skin Clinics, London, UK.
Dermatol Ther. 2020 Nov;33(6):e13976. doi: 10.1111/dth.13976. Epub 2020 Jul 27.
Rosacea is a common inflammatory skin disease characterized by erythema, episodes of flushing, and inflammatory lesions. It typically affects the face and is more prevalent among fair skin individuals affecting women more than men. Various treatments are available for rosacea with light-based therapies commonly used in the management of erythema. The use of intradermal botulinum toxin type-A has been reported to be beneficial in the treatment of rosacea-associated erythema and flushing with good results and a low side-effect profile. In this article, we present our experience on the successful combination of both pulsed dye laser and intradermal botulinum toxin type-A in erythema and flushing in 20 rosacea patients. In addition to subjective improvement, we measured the degree of erythema using a 3D Antera camera in order to quantify our results. We demonstrated high efficacy and satisfaction rate with this combined approach and a low side-effect profile. To our knowledge, the combination of laser and intradermal botulinum toxin in the management of rosacea has not been previously reported.
酒渣鼻是一种常见的炎症性皮肤疾病，其特征为红斑、阵发性潮红和炎症性皮损。它通常影响面部，在皮肤白皙的人群中更为普遍，女性比男性更为常见。有多种治疗酒渣鼻的方法，光疗通常用于治疗红斑。真皮内注射 A 型肉毒毒素已被报道对酒渣鼻相关红斑和潮红的治疗有益，且疗效良好，副作用低。在本文中，我们介绍了我们在 20 例酒渣鼻患者中成功联合应用脉冲染料激光和真皮内注射 A 型肉毒毒素治疗红斑和潮红的经验。除了主观改善，我们还使用 3D Antera 相机测量红斑程度，以量化我们的结果。我们证明了这种联合方法的高效性和高满意度，且副作用低。据我们所知，激光和真皮内注射肉毒毒素联合治疗酒渣鼻尚未见报道。
