Dayan Steven H, Pritzker Rachel N, Arkins John P
Department of Otolaryngology, University of Illinois, Chicago, IL, USA.
J Drugs Dermatol. 2012 Dec;11(12):e76-9.
Rosacea is a cutaneous condition with several clinical subtypes that are commonly seen in daily medical practice. There are many different treatment modalities for each of the physical findings associated with this disease, and all have varying results. As the use of onabotulinumtoxinA rises, its benefit in the treatment of a growing number of medical diseases increases. The authors report anecdotal evidence of patients with rosacea experiencing improved symptoms of erythema and flushing after treatment with intradermal, microdroplets of onabotulinumtoxinA. There were no adverse events reported for any of the treatments. The mechanism of action through a likely neurogenic component to vascular dysfunction, inflammation, and hypersebaceous activity is reviewed.
酒渣鼻是一种皮肤疾病，有几种临床亚型，在日常医疗实践中很常见。针对与该疾病相关的每种体征都有许多不同的治疗方式，且所有方式的效果各异。随着A型肉毒毒素使用的增加，其在治疗越来越多医学疾病中的益处也在增加。作者报告了酒渣鼻患者在接受皮内微滴注射A型肉毒毒素治疗后红斑和潮红症状改善的轶事证据。所有治疗均未报告不良事件。本文回顾了通过可能的神经源性成分作用于血管功能障碍、炎症和皮脂腺功能亢进的作用机制。
