The impact of the Bellagio Report on healthy agriculture, healthy nutrition, healthy people: scientific and policy aspects and the International Network of Centers for Genetics, Nutrition and Fitness for Health.

The Bellagio Report on Healthy Agriculture, Healthy Nutrition, Healthy People was the result of a meeting held at the Rockefeller Foundation Bellagio Center in the fall of 2012. The meeting was science based but policy oriented. The Bellagio Report concluded that: (1) sugar consumption, especially in the form of high-energy fructose in soft drinks, poses a major and insidious health threat, particularly for children; (2) current diets in most populations, albeit with regional differences, are deficient in omega-3 fatty acids but too high in omega-6 fatty acid intake, and (3) not all calories are the same since calories from different sources (i.e. glucose or fructose or omega-6 or omega-3 fatty acids) have different metabolic and neurohormonal effects. This paper summarizes the scientific progress and policy actions that have occurred in these three areas. Genetic variation in populations and gene-nutrient interactions are fundamental concepts that need to be taken into consideration in growth and development and in the prevention and management of chronic noncommunicable diseases since there is enormous variation in both the frequency of genetic variants and dietary composition worldwide. Furthermore, this paper updates the Bellagio Report in terms of the scientific and policy aspects, both of which have expanded over the past 2 years, and describes the progress made in establishing an International Network of Centers for Genetics, Nutrition and Fitness for Health.