Hasandokht Tolou, Farajzadegan Ziba, Siadat Zahra Dana, Paknahad Zamzam, Rajati Fatemeh
Department of Community Medicine, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Department of Community Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
J Res Med Sci. 2015 Jan;20(1):54-61.
Lifestyle factors such as weight, salt intake, and physical activity have shown to be important in treating hypertension. The object of this study was to describe feasibility and to assess the effectiveness of a multicomponent lifestyle intervention on high blood pressure (BP) of Iranian women.
This randomized controlled trial was conducted in four health centers by recruiting 161 women aged 35-65 years with high BP and randomizing them to a 4-week lifestyle modification (n = 80) or control group (n = 81). BP level and other health behavioral factors were assessed before and after the 4-week intervention and also after 6 months.
The mean systolic BP changed from 158.8 (±8.1) mmHg to 153.2 (±6.4) mmHg during 4-week and to 145.5 (±4.6)) mmHg after 6 months in the intervention group (P < 0.001). There was a significant difference between two groups of study after 4-week mean = 5.6 (confidence interval [CI] = 5.1-6.6) and 6 months follow mean (CI = 12.3-14.6).(P < 0.001) A significant correlation was detected between systolic BP (SBP) and diastolic BP (DBP) with weight, body mass index, waist circumference, salt intake, and physical activity level (P < 0.001). Stepwise regression analyses indicated that the weight, dietary salt intake, and physical activity level were significant predictors of SBP and DBP.
The results of this study suggest that lifestyle modification program is associated with improvements in BP level in Iranian women.
体重、盐摄入量和体育活动等生活方式因素已被证明在高血压治疗中很重要。本研究的目的是描述可行性，并评估多组分生活方式干预对伊朗女性高血压（BP）的有效性。
本随机对照试验在四个健康中心进行，招募了161名年龄在35 - 65岁的高血压女性，并将她们随机分为4周生活方式改善组（n = 80）或对照组（n = 81）。在4周干预前后以及6个月后评估血压水平和其他健康行为因素。
干预组在4周内平均收缩压从158.8（±8.1）mmHg降至153.2（±6.4）mmHg，6个月后降至145.5（±4.6）mmHg（P < 0.001）。4周后两组研究之间存在显著差异，平均值 = 5.6（置信区间[CI] = 5.1 - 6.6），6个月随访平均值（CI = 12.3 - 14.6）（P < 0.001）。收缩压（SBP）和舒张压（DBP）与体重、体重指数、腰围、盐摄入量和体育活动水平之间存在显著相关性（P < 0.001）。逐步回归分析表明，体重、饮食盐摄入量和体育活动水平是SBP和DBP的重要预测因素。
本研究结果表明，生活方式改善计划与伊朗女性血压水平的改善有关。
