酒精滥用是初次全髋关节置换术和全膝关节置换术后较差手术结局的独立危险因素。
Alcohol Misuse is an Independent Risk Factor for Poorer Postoperative Outcomes Following Primary Total Hip and Total Knee Arthroplasty.
作者信息
Best Matthew J, Buller Leonard T, Gosthe Raul G, Klika Alison K, Barsoum Wael K
机构信息
Department of Orthopaedic Surgery and Rehabilitation, University of Miami Miller School of Medicine, Miami, Florida.
Cleveland Clinic Department of Orthopaedic Surgery, Cleveland, Ohio.
出版信息
J Arthroplasty. 2015 Aug;30(8):1293-8. doi: 10.1016/j.arth.2015.02.028. Epub 2015 Feb 28.
The influence of alcohol misuse on outcomes following primary total hip (THA) or knee (TKA) arthroplasty is poorly understood. Using the National Hospital Discharge Survey, a cohort representative of 8,372,232 patients (without cirrhosis) who underwent THA or TKA between 1990 and 2007 was identified and divided into two groups: (1) those who misused alcohol (n=50,861) and (2) those who did not (n=8,321,371). Differences in discharge status, comorbidities and perioperative complications were analyzed. Compared to patients with no diagnosis of alcohol misuse, alcohol misusers were nine times more likely to leave against medical advice and had longer hospital stays (P<0.001). Alcohol misuse was independently associated with higher odds of in hospital complications (OR: 1.334, range: 1.307-1.361), surgery related complications (OR: 1.293, range: 1.218-1.373) and general medical complications (OR: 1.300, range: 1.273-1.327).
酒精滥用对初次全髋关节置换术（THA）或全膝关节置换术（TKA）术后结局的影响目前了解甚少。利用国家医院出院调查，确定了一个队列，该队列代表了1990年至2007年间接受THA或TKA手术的8372232名患者（无肝硬化），并将其分为两组：（1）酒精滥用者（n = 50861）和（2）非酒精滥用者（n = 8321371）。分析了出院状态、合并症和围手术期并发症的差异。与未诊断为酒精滥用的患者相比，酒精滥用者违背医嘱出院的可能性高9倍，住院时间更长（P<0.001）。酒精滥用与住院并发症（OR：1.334，范围：1.307 - 1.361）、手术相关并发症（OR：1.293，范围：1.218 - 1.373）和一般医疗并发症（OR：1.300，范围：1.273 - 1.327）的较高几率独立相关。
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